Micah G Donovan
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Explore the profile of Micah G Donovan including associated specialties, affiliations and a list of published articles.
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21
Citations
263
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Recent Articles
1.
Rachubinski A, Wallace E, Gurnee E, Enriquez-Estrada B, Worek K, Smith K, et al.
Elife
. 2024 Dec;
13.
PMID: 39737640
Background: Individuals with Down syndrome (DS), the genetic condition caused by trisomy 21 (T21), display clear signs of immune dysregulation, including high rates of autoimmunity and severe complications from infections....
2.
Donovan M, Rachubinski A, Smith K, Araya P, Waugh K, Enriquez-Estrada B, et al.
Cell Rep
. 2024 Aug;
43(8):114599.
PMID: 39120971
Down syndrome (DS), the genetic condition caused by trisomy 21 (T21), is characterized by delayed neurodevelopment, accelerated aging, and increased risk of many co-occurring conditions. Hypoxemia and dysregulated hematopoiesis have...
3.
Rachubinski A, Wallace E, Gurnee E, Estrada B, Worek K, Smith K, et al.
medRxiv
. 2024 Jul;
PMID: 38946973
Individuals with Down syndrome (DS), the genetic condition caused by trisomy 21 (T21), display clear signs of immune dysregulation, including high rates of autoimmune disorders and severe complications from infections....
4.
Donovan M, Eduthan N, Smith K, Britton E, Lyford H, Araya P, et al.
Nat Commun
. 2024 Jun;
15(1):5473.
PMID: 38942750
Individuals with Down syndrome, the genetic condition caused by trisomy 21, exhibit strong inter-individual variability in terms of developmental phenotypes and diagnosis of co-occurring conditions. The mechanisms underlying this variable...
5.
Andrysik Z, Donovan M
Transcription
. 2023 Dec;
14(3-5):89-91.
PMID: 38047544
No abstract available.
6.
Tatavosian R, Donovan M, Galbraith M, Duc H, Szwarc M, Joshi M, et al.
Cell Death Differ
. 2023 Jan;
30(4):952-965.
PMID: 36681780
The p53 transcription factor is a master regulator of cellular responses to stress that is commonly inactivated in diverse cancer types. Despite decades of research, the mechanisms by which p53...
7.
Donovan M, Galbraith M, Espinosa J
Sci Rep
. 2022 Dec;
12(1):22505.
PMID: 36577800
Transcriptional addiction is recognized as a valid therapeutic target in cancer, whereby the dependency of cancer cells on oncogenic transcriptional regulators may be pharmacologically exploited. However, a comprehensive understanding of...
8.
Freitas K, Belk J, Sotillo E, Quinn P, Ramello M, Malipatlolla M, et al.
Science
. 2022 Nov;
378(6620):eabn5647.
PMID: 36356142
T cells are the major arm of the immune system responsible for controlling and regressing cancers. To identify genes limiting T cell function, we conducted genome-wide CRISPR knockout screens in...
9.
Selmin O, Papoutsis A, Hazan S, Smith C, Greenfield N, Donovan M, et al.
Int J Mol Sci
. 2021 Jul;
22(13).
PMID: 34203196
: Concerns are emerging that a high-fat diet rich in -6 PUFA (-6HFD) may alter gut microbiome and increase the risk of intestinal disorders. Research is needed to model the...
10.
Stillwater B, Bull A, Romagnolo D, Neumayer L, Donovan M, Selmin O
Front Nutr
. 2020 Dec;
7:581388.
PMID: 33330580
Data from preclinical studies suggest a link between increased risk of breast cancer and exposure to bisphenols at doses below what the United States Food and Drug Administration (FDA) considers...