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Ross E Granrath

Explore the profile of Ross E Granrath including associated specialties, affiliations and a list of published articles. Areas
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Articles 15
Citations 344
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Recent Articles
1.
Rachubinski A, Wallace E, Gurnee E, Enriquez-Estrada B, Worek K, Smith K, et al.
Elife . 2024 Dec; 13. PMID: 39737640
Background: Individuals with Down syndrome (DS), the genetic condition caused by trisomy 21 (T21), display clear signs of immune dysregulation, including high rates of autoimmunity and severe complications from infections....
2.
Donovan M, Rachubinski A, Smith K, Araya P, Waugh K, Enriquez-Estrada B, et al.
Cell Rep . 2024 Aug; 43(8):114599. PMID: 39120971
Down syndrome (DS), the genetic condition caused by trisomy 21 (T21), is characterized by delayed neurodevelopment, accelerated aging, and increased risk of many co-occurring conditions. Hypoxemia and dysregulated hematopoiesis have...
3.
Rachubinski A, Wallace E, Gurnee E, Estrada B, Worek K, Smith K, et al.
medRxiv . 2024 Jul; PMID: 38946973
Individuals with Down syndrome (DS), the genetic condition caused by trisomy 21 (T21), display clear signs of immune dysregulation, including high rates of autoimmune disorders and severe complications from infections....
4.
Donovan M, Eduthan N, Smith K, Britton E, Lyford H, Araya P, et al.
Nat Commun . 2024 Jun; 15(1):5473. PMID: 38942750
Individuals with Down syndrome, the genetic condition caused by trisomy 21, exhibit strong inter-individual variability in terms of developmental phenotypes and diagnosis of co-occurring conditions. The mechanisms underlying this variable...
5.
Galbraith M, Rachubinski A, Smith K, Araya P, Waugh K, Enriquez-Estrada B, et al.
Sci Adv . 2023 Jun; 9(26):eadg6218. PMID: 37379383
Individuals with Down syndrome (DS) display chronic hyperactivation of interferon signaling. However, the clinical impacts of interferon hyperactivity in DS are ill-defined. Here, we describe a multiomics investigation of interferon...
6.
Waugh K, Minter R, Baxter J, Chi C, Galbraith M, Tuttle K, et al.
Nat Genet . 2023 Jun; 55(6):1034-1047. PMID: 37277650
Down syndrome (DS), the genetic condition caused by trisomy 21, is characterized by variable cognitive impairment, immune dysregulation, dysmorphogenesis and increased prevalence of diverse co-occurring conditions. The mechanisms by which...
7.
Araya P, Kinning K, Coughlan C, Smith K, Granrath R, Enriquez-Estrada B, et al.
Cell Rep . 2022 Dec; 41(13):111883. PMID: 36577365
Down syndrome (DS), the genetic condition caused by trisomy 21 (T21), is characterized by stunted growth, cognitive impairment, and increased risk of diverse neurological conditions. Although signs of lifelong neurodegeneration...
8.
Galbraith M, Kinning K, Sullivan K, Araya P, Smith K, Granrath R, et al.
Proc Natl Acad Sci U S A . 2022 Feb; 119(11). PMID: 35217532
The impacts of interferon (IFN) signaling on COVID-19 pathology are multiple, with both protective and harmful effects being documented. We report here a multiomics investigation of systemic IFN signaling in...
9.
Liggett L, Galbraith M, Smith K, Sullivan K, Granrath R, Enriquez-Estrada B, et al.
Blood Adv . 2021 Mar; 5(7):1791-1796. PMID: 33787858
No abstract available.
10.
Sullivan K, Galbraith M, Kinning K, Bartsch K, Levinsky N, Araya P, et al.
medRxiv . 2021 Mar; PMID: 33758879
COVID-19 pathology involves dysregulation of diverse molecular, cellular, and physiological processes. In order to expedite integrated and collaborative COVID-19 research, we completed multi-omics analysis of hospitalized COVID-19 patients including matched...