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Micah E Tepora

Explore the profile of Micah E Tepora including associated specialties, affiliations and a list of published articles. Areas
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Articles 6
Citations 285
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Recent Articles
1.
Vieira M, Palm A, Stamper C, Tepora M, Nguyen K, Pham T, et al.
PLoS Pathog . 2023 Aug; 19(8):e1011603. PMID: 37624867
Antibodies result from the competition of B cell lineages evolving under selection for improved antigen recognition, a process known as affinity maturation. High-affinity antibodies to pathogens such as HIV, influenza,...
2.
Guthmiller J, Han J, Utset H, Li L, Lan L, Henry C, et al.
Nature . 2021 Dec; 602(7896):314-320. PMID: 34942633
Broadly neutralizing antibodies that target epitopes of haemagglutinin on the influenza virus have the potential to provide near universal protection against influenza virus infection. However, viral mutants that escape broadly...
3.
Guthmiller J, Han J, Li L, Freyn A, Liu S, Stovicek O, et al.
Sci Transl Med . 2021 Jun; 13(596). PMID: 34078743
Broadly neutralizing antibodies are critical for protection against both drifted and shifted influenza viruses. Here, we reveal that first exposure to the 2009 pandemic H1N1 influenza virus recalls memory B...
4.
Dugan H, Guthmiller J, Arevalo P, Huang M, Chen Y, Neu K, et al.
Sci Transl Med . 2020 Dec; 12(573). PMID: 33298562
Humans are repeatedly exposed to variants of influenza virus throughout their lifetime. As a result, preexisting influenza-specific memory B cells can dominate the response after infection or vaccination. Memory B...
5.
Bernstein D, Guptill J, Naficy A, Nachbagauer R, Berlanda-Scorza F, Feser J, et al.
Lancet Infect Dis . 2019 Oct; 20(1):80-91. PMID: 31630990
Background: Influenza viruses cause substantial annual morbidity and mortality globally. Current vaccines protect against influenza only when well matched to the circulating strains. However, antigenic drift can cause considerable mismatches...
6.
Neu K, Guthmiller J, Huang M, La J, Vieira M, Kim K, et al.
J Clin Invest . 2018 Nov; 129(1):93-105. PMID: 30457979
Vaccines are among the most effective public health tools for combating certain infectious diseases such as influenza. The role of the humoral immune system in vaccine-induced protection is widely appreciated;...