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Meritxell Gironella

Explore the profile of Meritxell Gironella including associated specialties, affiliations and a list of published articles. Areas
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Articles 56
Citations 1947
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Recent Articles
21.
Benyamine A, Loncle C, Foucher E, Blazquez J, Castanier C, Chretien A, et al.
Oncoimmunology . 2018 Jan; 7(1):e1372080. PMID: 29296524
Vγ9Vδ2 T cells are anti-tumor immune effectors of growing interest in cancer including Pancreatic Ductal Adenocarcinoma (PDAC), an especially aggressive cancer characterized by a hypoxic and nutrient-starved immunosuppressive microenvironment. Since...
22.
Nigri J, Gironella M, Bressy C, Vila-Navarro E, Roques J, Lac S, et al.
Cell Mol Life Sci . 2017 Jun; 74(22):4231-4243. PMID: 28656348
Pancreatic ductal adenocarcinoma (PDA) is a fatal and insidious malignant disease for which clinicians' tools are restricted by the current limits in knowledge of how tumor and stromal cells act...
23.
Bonjoch L, Gironella M, Iovanna J, Closa D
Sci Rep . 2017 Jun; 7(1):3143. PMID: 28600520
Extracellular vesicles (EVs), including exosomes and microvesicles, are nano-sized membrane vesicles containing proteins and nucleic acids, which act as intercellular messengers. They play an important role in a variety of...
24.
Planque C, Rajabi F, Grillet F, Finetti P, Bertucci F, Gironella M, et al.
Oncotarget . 2016 Jul; 7(35):56558-56573. PMID: 27448961
Colorectal cancer lethality usually results from post-treatment relapse in the majority of stage II-IV patients, due to the enhanced resistance of Cancer Stem Cells (CSCs). Here, we show that the...
25.
Vila-Navarro E, Vila-Casadesus M, Moreira L, Duran-Sanchon S, Sinha R, Gines A, et al.
Ann Surg . 2016 May; 265(6):1226-1234. PMID: 27232245
Objective: The aim of our study was to analyze the miRNome of pancreatic ductal adenocarcinoma (PDAC) and its preneoplastic lesion intraductal papillary mucinous neoplasm (IPMN), to find new microRNA (miRNA)-based...
26.
Vila-Casadesus M, Gironella M, Lozano J
PLoS One . 2016 Mar; 11(3):e0151127. PMID: 26967326
MicroRNAs (miRNAs) are small RNAs that regulate the expression of target mRNAs by specific binding on the mRNA 3'UTR and promoting mRNA degradation in the majority of cases. It is...
27.
Secq V, Mallmann C, Gironella M, Lopez B, Closa D, Garcia S, et al.
J Cell Physiol . 2015 Aug; 231(1):2. PMID: 26280560
No abstract available.
28.
Vargas T, Moreno-Rubio J, Herranz J, Cejas P, Molina S, Gonzalez-Vallinas M, et al.
Oncotarget . 2015 Mar; 6(9):7348-63. PMID: 25749516
Lipid metabolism plays an essential role in carcinogenesis due to the requirements of tumoral cells to sustain increased structural, energetic and biosynthetic precursor demands for cell proliferation. We investigated the...
29.
Bofill-De Ros X, Gironella M, Fillat C
Mol Ther . 2014 Jun; 22(9):1665-77. PMID: 24895996
Oncolytic virotherapy shows promise for pancreatic ductal adenocarcinoma (PDAC) treatment, but there is the need to minimize associated-toxicities. In the current work, we engineered artificial target sites recognized by miR-216a...
30.
Aguado-Llera D, Hamidi T, Domenech R, Pantoja-Uceda D, Gironella M, Santoro J, et al.
PLoS One . 2013 Nov; 8(10):e78101. PMID: 24205110
The stress protein Nupr1 is a highly basic, multifunctional, intrinsically disordered protein (IDP). MSL1 is a histone acetyl transferase-associated protein, known to intervene in the dosage compensation complex (DCC). In...