Mercedes Costell
Overview
Explore the profile of Mercedes Costell including associated specialties, affiliations and a list of published articles.
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Articles
33
Citations
1137
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Recent Articles
1.
Guerrero-Barbera G, Burday N, Costell M
Front Cell Dev Biol
. 2024 Apr;
12:1363004.
PMID: 38660622
The extracellular matrix (ECM) is a complex network of proteins and glycans, dynamically remodeled and specifically tailored to the structure/function of each organ. The malignant transformation of cancer cells is...
2.
Gimeno-LLuch I, Benito-Jardon M, Guerrero-Barbera G, Burday N, Costell M
Cells
. 2022 Jul;
11(13).
PMID: 35805184
Skin is constantly exposed to injuries that are repaired with different outcomes, either regeneration or scarring. Scars result from fibrotic processes modulated by cellular physical forces transmitted by integrins. Fibronectin...
3.
Krenn P, Montanez E, Costell M, Fassler R
Curr Top Dev Biol
. 2022 May;
149:203-261.
PMID: 35606057
Hematopoietic stem cells (HSCs), the apex of the hierarchically organized blood cell production system, are generated in the yolk sac, aorta-gonad-mesonephros region and placenta of the developing embryo. To maintain...
4.
Barba-Aliaga M, Mena A, Espinoza V, Apostolova N, Costell M, Alepuz P
J Cell Sci
. 2021 Aug;
134(18).
PMID: 34447991
Translation of mRNAs that encode peptide sequences with consecutive prolines (polyproline) requires the conserved and essential elongation factor eIF5A to facilitate the formation of peptide bonds. It has been shown...
5.
Benito-Jardon M, Strohmeyer N, Otega-Sanchis S, Bharadwaj M, Moser M, Muller D, et al.
J Cell Biol
. 2020 Dec;
220(1).
PMID: 33306093
No abstract available.
6.
αv-Class integrin binding to fibronectin is solely mediated by RGD and unaffected by an RGE mutation
Benito-Jardon M, Strohmeyer N, Ortega-Sanchis S, Bharadwaj M, Moser M, Muller D, et al.
J Cell Biol
. 2020 Nov;
219(12).
PMID: 33141174
Fibronectin (FN) is an essential glycoprotein of the extracellular matrix; binds integrins, syndecans, collagens, and growth factors; and is assembled by cells into complex fibrillar networks. The RGD motif in...
7.
Rico P, Rodrigo-Navarro A, de la Pena M, Moulisova V, Costell M, Salmeron-Sanchez M
Adv Biosyst
. 2020 Jul;
3(1):e1800220.
PMID: 32627349
Boron ion is essential in metabolism and its concentration is regulated by ion-channel NaBC1. NaBC1 mutations cause corneal dystrophies such as Harboyan syndrome. Here a 3D molecular model for NaBC1...
8.
Ngandu Mpoyi E, Cantini M, Sin Y, Fleming L, Zhou D, Costell M, et al.
Biomaterials
. 2020 May;
252:120090.
PMID: 32413593
Basement membranes (BMs) are specialised extracellular matrices that provide structural support to tissues as well as influence cell behaviour and signalling. Mutations in COL4A1/COL4A2, a major BM component, cause a...
9.
Altstatter J, Hess M, Costell M, Montanez E
PLoS One
. 2020 Mar;
15(3):e0230380.
PMID: 32163511
Epidermal morphogenesis and hair follicle (HF) development depend on the ability of keratinocytes to adhere to the basement membrane (BM) and migrate along the extracellular matrix. Integrins are cell-matrix receptors...
10.
Pinto-Costa R, Sousa S, Leite S, Nogueira-Rodrigues J, Ferreira da Silva T, Machado D, et al.
J Clin Invest
. 2020 Jan;
130(4):2024-2040.
PMID: 31945017
After trauma, regeneration of adult CNS axons is abortive, causing devastating neurologic deficits. Despite progress in rehabilitative care, there is no effective treatment that stimulates axonal growth following injury. Using...