Meng-Xing Huang
Overview
Explore the profile of Meng-Xing Huang including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
12
Citations
54
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Zhao Z, Jiang M, Huang M, Yang Y, Feng L, Zhang C, et al.
J Med Chem
. 2024 Apr;
67(10):8309-8322.
PMID: 38669059
Liver fibrosis is a common pathological feature of most chronic liver diseases with no effective drugs available. Phosphodiesterase 1 (PDE1), a subfamily of the PDE super enzyme, might work as...
2.
Qiu M, Wang C, Wu Z, Zhao Q, Zhao Z, Huang C, et al.
Signal Transduct Target Ther
. 2023 Sep;
8(1):370.
PMID: 37735150
Epstein‒Barr virus (EBV)-associated gastric cancer (GC) manifests an intriguing immunotherapy response. However, the cellular basis for EBV-imprinted tumour immunity and on-treatment response remains undefined. This study aimed to finely characterize...
3.
Long J, Yang S, Huang M, Luo P, Li L, Tsuneyama K, et al.
J Pathol
. 2023 Feb;
260(2):222-234.
PMID: 36853094
Autoimmune regulator (Aire) and TGF-β signaling play important roles in central tolerance and peripheral tolerance, respectively, by eliminating or suppressing the activity of autoreactive T cells. We previously demonstrated that...
4.
Yin T, Huang M, Wang F, Jiang Y, Long J, Li L, et al.
Front Genet
. 2022 Sep;
13:943849.
PMID: 36046245
Tumor-derived lactate can modulate the function of infiltrating immune cells to establish an immunosuppressive microenvironment that favors tumor progression. However, possible effects of lactate-related genes (LRGs) on the tumor microenvironment...
5.
Huang M, Chen Y, Liu R, Huang Y, Zhang C
Molecules
. 2022 Jun;
27(11).
PMID: 35684390
Dipyridamole, apart from its well-known antiplatelet and phosphodiesterase inhibitory activities, is a promising old drug for the treatment of pulmonary fibrosis. However, dipyridamole shows poor pharmacokinetic properties with a half-life...
6.
Yang S, Huang M, Sun Y, Li L, Bian Z, Long J, et al.
J Immunol Methods
. 2022 Jun;
507:113294.
PMID: 35675842
This 33-color panel delineates immune phenotypes of the major lymphocyte subsets in murine tissues. The panel identifies surface markers for cell activation, differentiation, and exhaustion, and chemokine receptors, in CD4...
7.
Huang M, Tian Y, Han C, Liu R, Xie X, Yuan Y, et al.
J Med Chem
. 2022 Jun;
65(12):8444-8455.
PMID: 35666471
Our previous research demonstrated that phosphodiesterase-1 (PDE1) could work as a potential target against idiopathic pulmonary fibrosis. Nimodipine, a calcium antagonist commonly used to improve hypertension, was reported to have...
8.
Yang S, Long J, Huang M, Luo P, Bian Z, Xu Y, et al.
Front Immunol
. 2021 Oct;
12:711980.
PMID: 34594327
Regulatory B cells (Breg) are considered as immunosuppressive cells. Different subsets of Breg cells have been identified both in human beings and in mice. However, there is a lack of...
9.
Zhang B, Huang Y, Zhang S, Huang M, Zhang C, Luo H
Bioorg Chem
. 2021 Jun;
114:105104.
PMID: 34186466
Phosphodiesterase-1 (PDE1) is a promising drug target closely related to central and peripheral diseases. With the assistance of molecular docking and dynamics simulations, we designed and synthesized a novel series...
10.
Huang M, Yang S, Luo P, Long J, Liu Q, Wang J, et al.
J Leukoc Biol
. 2021 May;
110(6):1121-1130.
PMID: 34047390
The data demonstrated that a transgenic murine model of primary biliary cholangitis (PBC), expressing dominant negative TGF-β receptor Ⅱ (dnTGFβRⅡ) under the CD4 promoter, showed similarity to PBC patients that...