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Melissa P Upton

Explore the profile of Melissa P Upton including associated specialties, affiliations and a list of published articles. Areas
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Articles 71
Citations 1169
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Recent Articles
21.
Chen C, Zhang Y, Loomis M, Upton M, Lohavanichbutr P, Houck J, et al.
PLoS One . 2015 Aug; 10(8):e0135074. PMID: 26247464
Oral squamous cell cancer of the oral cavity and oropharynx (OSCC) is associated with high case-fatality. For reasons that are largely unknown, patients with the same clinical and pathologic staging...
22.
Choi W, Emond M, Rabinovitch P, Ahn J, Upton M, Westerhoff M
Clin Transl Gastroenterol . 2015 Mar; 6:e81. PMID: 25761942
Background: Dysplasia arising from Barrett's esophagus precedes esophageal adenocarcinoma (EAC). Cases that are difficult to diagnose as dysplastic, especially in the setting of inflammation, may be designated "indefinite for dysplasia...
23.
Passarelli M, Newcomb P, Makar K, Burnett-Hartman A, Potter J, Upton M, et al.
Cancer Causes Control . 2015 Jan; 26(3):467-73. PMID: 25618792
Purpose: Studies linking cholesterol levels to the development of colorectal neoplasia are inconsistent, and Mendelian randomization has been suggested as a way to help avoid problems with confounding and reverse...
24.
Adams S, Newcomb P, Burnett-Hartman A, Wurscher M, Mandelson M, Upton M, et al.
PLoS One . 2014 Oct; 9(10):e108668. PMID: 25286412
Background: MicroRNAs (miRNAs) are regulatory RNAs, stable in circulation, and implicated in colorectal cancer (CRC) etiology and progression. Therefore they are promising as early detection biomarkers of colorectal neoplasia. However,...
25.
Al-Haddad S, Chang A, De Hertogh G, Grin A, Langer R, Sagaert X, et al.
Ann N Y Acad Sci . 2014 Oct; 1325:211-25. PMID: 25266027
The following, from the 12th OESO World Conference: Cancers of the Esophagus, includes commentaries on the clinical differences between carcinomas arising slightly above, slightly below, and within the gastroesophageal junction...
26.
Baruah A, Buttar N, Chandra R, Chen X, Clemons N, Compare D, et al.
Ann N Y Acad Sci . 2014 Oct; 1325:170-86. PMID: 25266024
The following, from the 12th OESO World Conference: Cancers of the Esophagus, includes commentaries on translational research on Barrett's esophagus that address evidence for genetic instability in esophageal cancer; the...
27.
Burnett-Hartman A, Newcomb P, Hutter C, Peters U, Passarelli M, Schwartz M, et al.
Am J Epidemiol . 2014 May; 180(2):223-32. PMID: 24875374
We conducted a case-control study of the association between subsets of colorectal polyps, including adenomas and serrated polyps, and single-nucleotide polymorphisms (SNPs) related to colorectal cancer through prior genome-wide association...
28.
Zhang X, Xu C, Mitchell R, Zhang B, Zhao D, Li Y, et al.
Neoplasia . 2014 Jan; 15(12):1371-8. PMID: 24403859
Head and neck squamous cell carcinoma (HNSCC) is characterized by significant genomic instability that could lead to clonal diversity. Intratumor clonal heterogeneity has been proposed as a major attribute underlying...
29.
Chou J, Fitzgibbon M, Mortales C, Towlerton A, Upton M, Yeung R, et al.
PLoS One . 2013 Nov; 8(11):e79874. PMID: 24278200
Xenografts of human colorectal cancer (CRC) in immune-deficient mice have great potential for accelerating the study of tumor biology and therapy. We evaluated xenografts established in NOD/scid/IL2Rγ-null mice from the...
30.
Appelman H, Streutker C, Vieth M, Neumann H, Neurath M, Upton M, et al.
Ann N Y Acad Sci . 2013 Oct; 1300:144-165. PMID: 24117640
This paper presents commentaries on the microscopic morphology of esophageal squamous epithelium; the frequency of duplication of the muscularis mucosae (MM) in Barrett's esophagus (BE); the significance of multilayered epithelium;...