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John R Houck

Explore the profile of John R Houck including associated specialties, affiliations and a list of published articles. Areas
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Articles 14
Citations 277
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Recent Articles
1.
Chen C, Lohavanichbutr P, Zhang Y, Houck J, Upton M, Abedi-Ardekani B, et al.
Oral Oncol . 2019 Dec; 100:104487. PMID: 31835136
Objectives: To test the performance of an oral cancer prognostic 13-gene signature for the prediction of survival of patients diagnosed with HPV-negative and p16-negative oral cavity cancer. Materials And Methods:...
2.
Doherty J, Grieshober L, Houck J, Barnett M, de Dieu Tapsoba J, Thornquist M, et al.
Cancer Epidemiol Biomarkers Prev . 2018 May; 27(7):829-837. PMID: 29743162
Accumulating evidence suggests that short telomere length is associated with increased overall mortality, but the relationship with cancer mortality is less clear. We examined whether telomere length (global, and chromosome...
3.
Doherty J, Grieshober L, Houck J, Barnett M, de Dieu Tapsoba J, Thornquist M, et al.
Br J Cancer . 2018 Apr; 118(11):1513-1517. PMID: 29670295
Background: Telomeres protect cells from genomic instability. We examined telomere length and lung cancer risk prospectively in heavy smokers. Methods: In a nested case-control study with 709 cases and 1313...
4.
Feng L, Houck J, Lohavanichbutr P, Chen C
Oncotarget . 2017 Apr; 8(19):31521-31531. PMID: 28415559
Oral cavity and oropharyngeal squamous cell carcinoma (OSCC) is a major cancer type in the head and neck region. To better understand the roles long non-coding RNA (lncRNA) play in...
5.
Chen C, Zhang Y, Loomis M, Upton M, Lohavanichbutr P, Houck J, et al.
PLoS One . 2015 Aug; 10(8):e0135074. PMID: 26247464
Oral squamous cell cancer of the oral cavity and oropharynx (OSCC) is associated with high case-fatality. For reasons that are largely unknown, patients with the same clinical and pathologic staging...
6.
Xu C, Wang P, Liu Y, Zhang Y, Fan W, Upton M, et al.
PLoS Genet . 2013 Jan; 9(1):e1003169. PMID: 23341773
In oral squamous cell carcinoma (OSCC), metastasis to lymph nodes is associated with a 50% reduction in 5-year survival. To identify a metastatic gene set based on DNA copy number...
7.
Serrano N, Xu C, Liu Y, Wang P, Fan W, Upton M, et al.
Otolaryngol Head Neck Surg . 2012 Apr; 147(3):501-8. PMID: 22470160
Objective: To better understand possible mechanisms involved in the dysregulation of gene expression unique to oral squamous cell carcinoma (OSCC) metastasis, the investigators examined the differential expression of microRNAs (miRNAs)...
8.
Stott-Miller M, Houck J, Lohavanichbutr P, Mendez E, Upton M, Futran N, et al.
Cancer Epidemiol Biomarkers Prev . 2011 Oct; 20(12):2628-36. PMID: 21960692
Background: The matrix metalloproteinases (MMP) cause degradation of the extracellular matrix and basement membranes, and thus may play a key role in cancer development. Methods: In our search for biomarkers...
9.
Mendez E, Lohavanichbutr P, Fan W, Houck J, Rue T, Doody D, et al.
Clin Cancer Res . 2011 Feb; 17(8):2466-73. PMID: 21300763
Purpose: To determine the differential gene expression between oral squamous cell carcinoma (OSCC) with and without metastasis to cervical lymph nodes and to assess prediction of nodal metastasis by using...
10.
Xu C, Liu Y, Wang P, Fan W, Rue T, Upton M, et al.
Mol Cancer . 2010 Jun; 9:143. PMID: 20537188
Background: Lymphotropism in oral squamous cell carcinoma (OSCC) is one of the most important prognostic factors of 5-year survival. In an effort to identify genes that may be responsible for...