Melissa Lim
Overview
Explore the profile of Melissa Lim including associated specialties, affiliations and a list of published articles.
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24
Citations
326
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Recent Articles
1.
Oliver K, Granero A, Berankova A, Miller C, Hindson C, La Haye C, et al.
Neurooncol Pract
. 2025 Feb;
12(1):5-18.
PMID: 39917767
Across the globe, significant inequities in brain tumor treatment, care, and support perpetuate. Identifying and addressing these unmet needs in the context of patients' rights is crucial to reducing inequalities...
2.
Yau E, Lim M, Qaiyum Z, Boroojeni S, Tang M, Pacheco A, et al.
Biomolecules
. 2024 Nov;
14(11).
PMID: 39595563
Spondyloarthritis (SpA) describes a group of diseases characterized by chronic inflammation in the spine and peripheral joints. While pathogenesis is still unclear, proinflammatory gut-derived immune cells have been identified in...
3.
Pacheco A, Maguire S, Qaiyum Z, Tang M, Bridger A, Lim M, et al.
Arthritis Rheumatol
. 2024 Aug;
77(1):34-46.
PMID: 39160761
Objective: Axial spondyloarthritis (axSpA) is an inflammatory disease in which overactive interleukin (IL)-17A-producing cells are implicated in a central role. Therapeutically, biologics that target IL-17A, such as secukinumab, have demonstrated...
4.
Lim M, Cong T, Orr L, Toriki E, Kile A, Papatzimas J, et al.
ACS Cent Sci
. 2024 Jul;
10(7):1318-1331.
PMID: 39071058
Targeted protein degradation with monovalent molecular glue degraders is a powerful therapeutic modality for eliminating disease causing proteins. However, rational design of molecular glue degraders remains challenging. In this study,...
5.
Tavasolian F, Lively S, Pastrello C, Tang M, Lim M, Pacheco A, et al.
Ann Rheum Dis
. 2023 Aug;
82(11):1429-1443.
PMID: 37532285
Introduction: Recent advances in understanding the biology of ankylosing spondylitis (AS) using innovative genomic and proteomic approaches offer the opportunity to address current challenges in AS diagnosis and management. Altered...
6.
Emerson L, Pellicano E, Monk R, Lim M, Heaton J, McLay L
Autism
. 2023 Feb;
:13623613231155954.
PMID: 36802870
We aimed to document the areas of autism research that have previously been funded in Aotearoa New Zealand. We searched for research grants awarded to autism research in Aotearoa New...
7.
Matsumoto Y, Dimitriou I, La Rose J, Lim M, Camilleri S, Law N, et al.
J Clin Invest
. 2022 Apr;
132(7).
PMID: 35362478
Dysregulation of Toll-like receptor (TLR) signaling contributes to the pathogenesis of autoimmune diseases. Here, we provide genetic evidence that tankyrase, a member of the poly(ADP-ribose) polymerase (PARP) family, negatively regulates...
8.
Sims H, de Andrade Horn P, Isshiki R, Lim M, Xu Y, Grubbs R, et al.
Angew Chem Int Ed Engl
. 2021 Dec;
61(5):e202115633.
PMID: 34870881
A concise and stereoselective total synthesis of the clinically relevant tricyclic prostaglandin D metabolite (tricyclic-PGDM) methyl ester in racemic form was accomplished in eight steps from a readily available known...
9.
Nakamura A, Zeng F, Nakamura S, Reid K, Gracey E, Lim M, et al.
Sci Transl Med
. 2021 Oct;
13(616):eabg1210.
PMID: 34669443
Spondyloarthritis (SpA), a type 3 immunity-mediated inflammatory arthritis, is a systemic rheumatic disease that primarily affects the joints, spine, gut, skin, and eyes. Macrophage migration inhibitory factor (MIF) is a...
10.
Qaiyum Z, Lim M, Inman R
Semin Immunopathol
. 2021 Feb;
43(2):173-192.
PMID: 33625549
The strong genetic and clinical overlaps between spondyloarthritis (SpA) and inflammatory bowel disease (IBD) have placed much needed focus on the gut-joint axis of inflammation in SpA, leading to three...