Melissa Cipolla
Overview
Explore the profile of Melissa Cipolla including associated specialties, affiliations and a list of published articles.
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Articles
37
Citations
6249
Followers
0
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Recent Articles
1.
Viant C, Wirthmiller T, ElTanbouly M, Chen S, Kara E, Cipolla M, et al.
J Exp Med
. 2024 Apr;
221(5).
PMID: 38683188
No abstract available.
2.
Hagglof T, Cipolla M, Loewe M, Chen S, Kara E, Mesin L, et al.
Cell
. 2024 Apr;
187(11):2893.
PMID: 38657600
No abstract available.
3.
ElTanbouly M, Ramos V, MacLean A, Chen S, Loewe M, Steinbach S, et al.
J Exp Med
. 2024 Jan;
221(2).
PMID: 38226977
No abstract available.
4.
ElTanbouly M, Ramos V, MacLean A, Chen S, Loewe M, Steinbach S, et al.
J Exp Med
. 2023 Nov;
221(1).
PMID: 37938344
Protective immune responses to many pathogens depend on the development of high-affinity antibody-producing plasma cells (PC) in germinal centers (GCs). Transgenic models suggest that there is a stringent affinity-based barrier...
5.
Chen S, Oliveira T, Gazumyan A, Cipolla M, Nussenzweig M
Immunity
. 2023 Mar;
56(3):547-561.e7.
PMID: 36882061
Germinal centers (GCs) are sites of B cell clonal expansion, diversification, and antibody affinity selection. This process is limited and directed by T follicular helper cells that provide helper signals...
6.
Hagglof T, Cipolla M, Loewe M, Chen S, Mesin L, Hartweger H, et al.
Cell
. 2022 Dec;
186(1):147-161.e15.
PMID: 36565698
Antibody responses are characterized by increasing affinity and diversity over time. Affinity maturation occurs in germinal centers by a mechanism that involves repeated cycles of somatic mutation and selection. How...
7.
Schaefer-Babajew D, Wang Z, Muecksch F, Cho A, Loewe M, Cipolla M, et al.
Nature
. 2022 Dec;
613(7945):735-742.
PMID: 36473496
Feedback inhibition of humoral immunity by antibodies was first documented in 1909. Subsequent studies showed that, depending on the context, antibodies can enhance or inhibit immune responses. However, little is...
8.
Agudelo M, Muecksch F, Schaefer-Babajew D, Cho A, DaSilva J, Bednarski E, et al.
J Exp Med
. 2022 Jul;
219(9).
PMID: 35796685
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to be a global problem in part because of the emergence of variants of concern that evade neutralization by antibodies elicited by...
9.
Wang Z, Muecksch F, Cho A, Gaebler C, Hoffmann H, Ramos V, et al.
Immunity
. 2022 Apr;
55(6):998-1012.e8.
PMID: 35447092
SARS-CoV-2 infection or vaccination produces neutralizing antibody responses that contribute to better clinical outcomes. The receptor-binding domain (RBD) and the N-terminal domain (NTD) of the spike trimer (S) constitute the...
10.
Jurczyszak D, Manganaro L, Buta S, Gruber C, Martin-Fernandez M, Taft J, et al.
PLoS Pathog
. 2022 Mar;
18(3):e1010405.
PMID: 35333911
Type I interferons (IFN-Is) are a group of potent inflammatory and antiviral cytokines. They induce IFN stimulated genes (ISGs), which act as proinflammatory mediators, antiviral effectors, and negative regulators of...