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Melanie Katz

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Articles 9
Citations 999
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Recent Articles
1.
Hung M, Sadri M, Katz M, Schwartz C, Mohajeri A
Dent J (Basel) . 2024 Oct; 12(10). PMID: 39452443
Introduction: Regenerative medicine is revolutionizing oral and maxillofacial surgeries with stem cells, particularly mesenchymal stem cells, for tissue and bone regeneration. Despite promising results, human trials are limited. A systematic...
2.
Shaver N, Katz M, Asamoah G, Linkins L, Abdelkader W, Beck A, et al.
Vaccine . 2023 Sep; 41(43):6411-6418. PMID: 37718186
Background: It is evident that COVID-19 will remain a public health concern in the coming years, largely driven by variants of concern (VOC). It is critical to continuously monitor vaccine...
3.
Rajbhandari P, Thomas B, Feng A, Hong C, Wang J, Vergnes L, et al.
Cell . 2017 Dec; 172(1-2):218-233.e17. PMID: 29249357
Signaling pathways that promote adipose tissue thermogenesis are well characterized, but the limiters of energy expenditure are largely unknown. Here, we show that ablation of the anti-inflammatory cytokine IL-10 improves...
4.
Crosby J, Zhao C, Jiang C, Bai D, Katz M, Greenlee S, et al.
J Cyst Fibros . 2017 May; 16(6):671-680. PMID: 28539224
Background: Epithelial sodium channel (ENaC, Scnn1) hyperactivity in the lung leads to airway surface dehydration and mucus accumulation in cystic fibrosis (CF) patients and in mice with CF-like lung disease....
5.
Sallam T, Jones M, Gilliland T, Zhang L, Wu X, Eskin A, et al.
Nature . 2016 Jun; 534(7605):124-8. PMID: 27251289
Liver X receptors (LXRs) are transcriptional regulators of cellular and systemic cholesterol homeostasis. Under conditions of excess cholesterol, LXR activation induces the expression of several genes involved in cholesterol efflux,...
6.
Jiang J, Zhu Q, Gendron T, Saberi S, McAlonis-Downes M, Seelman A, et al.
Neuron . 2016 Apr; 90(3):535-50. PMID: 27112497
Hexanucleotide expansions in C9ORF72 are the most frequent genetic cause of amyotrophic lateral sclerosis and frontotemporal dementia. Disease mechanisms were evaluated in mice expressing C9ORF72 RNAs with up to 450...
7.
Burel S, Hart C, Cauntay P, Hsiao J, Machemer T, Katz M, et al.
Nucleic Acids Res . 2015 Nov; 44(5):2093-109. PMID: 26553810
High affinity antisense oligonucleotides (ASOs) containing bicylic modifications (BNA) such as locked nucleic acid (LNA) designed to induce target RNA cleavage have been shown to have enhanced potency along with...
8.
Huang L, Damle S, Booten S, Singh P, Sabripour M, Hsu J, et al.
PLoS One . 2015 Jul; 10(7):e0132798. PMID: 26207833
Liver regeneration after partial hepatectomy (PHx) is a complex and well-orchestrated biological process in which synchronized cell proliferation is induced in response to the loss of liver mass. To define...
9.
Lagier-Tourenne C, Baughn M, Rigo F, Sun S, Liu P, Li H, et al.
Proc Natl Acad Sci U S A . 2013 Oct; 110(47):E4530-9. PMID: 24170860
Expanded hexanucleotide repeats in the chromosome 9 open reading frame 72 (C9orf72) gene are the most common genetic cause of ALS and frontotemporal degeneration (FTD). Here, we identify nuclear RNA...