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Shuling Guo

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Articles 92
Citations 2799
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Recent Articles
1.
Prajapati M, Zhang J, Chong G, Chiu L, Mercadante C, Kowalski H, et al.
Cell Mol Gastroenterol Hepatol . 2025 Mar; :101489. PMID: 40024532
Background And Aims: SLC11A2 (DMT1) and SLC40A1 (ferroportin) are essential for dietary iron absorption, but their role in manganese transport is debated. SLC30A10 deficiency causes severe manganese excess due to...
2.
Armisen J, Rauschecker M, Sarv J, Liljeblad M, Wernevik L, Niazi M, et al.
J Hepatol . 2025 Jan; PMID: 39798707
Background & Aims: A common genetic variant (rs738409) encoding isoleucine to methionine at position 148 in the PNPLA3 protein is a determinant of hepatic steatosis, inflammation, fibrosis, cirrhosis, and liver-related...
3.
Yin C, Fu L, Guo S, Liang Y, Shu T, Shao W, et al.
Adv Sci (Weinh) . 2024 Dec; 12(7):e2409398. PMID: 39716898
Fibroblast activation protein (FAP), predominantly expressed in activated fibroblasts, plays a key role in inflammatory bone diseases, but its role in periodontitis remains unclear. Accordingly, this study identified a positive...
4.
Sutharsan S, Fischer R, Gleiber W, Horsley A, Crosby J, Guo S, et al.
ERJ Open Res . 2024 Sep; 10(4). PMID: 39286058
Background: Hyperactivity of epithelial sodium channel (ENaC) with increased sodium absorption is a feature of cystic fibrosis (CF). ION-827359 is a 2.5-generation antisense oligonucleotide targeted to reduce ENaC protein. This...
5.
Prajapati M, Zhang J, Chong G, Chiu L, Mercadante C, Kowalski H, et al.
bioRxiv . 2024 Jul; PMID: 39071439
SLC30A10 deficiency is a disease of severe manganese excess attributed to loss of SLC30A10-dependent manganese excretion via the gastrointestinal tract. Patients develop dystonia, cirrhosis, and polycythemia. They are treated with...
6.
Zeng X, Xu Y, Guo S, Xiao Y, Yuan J, Yang L
IUCrdata . 2024 May; 9(Pt 4):x240360. PMID: 38721001
The mol-ecule of the title NCS pincer -heterocyclic carbene palladium(II) complex, [PdBr(CHNS)]Br, exhibits a slightly distorted square-planar coordination at the palladium(II) atom, with the five-membered chelate ring nearly planar. The...
7.
Guerra A, Hamilton N, Rivera A, Demsko P, Guo S, Rivella S
Am J Hematol . 2024 Apr; 99(7):1300-1312. PMID: 38659383
A recently approved drug that induces erythroid cell maturation (luspatercept) has been shown to improve anemia and reduce the need for blood transfusion in non-transfusion-dependent as well as transfusion-dependent β-thalassemia...
8.
Prajapati M, Zhang J, Chiu L, Chong G, Mercadante C, Kowalski H, et al.
JCI Insight . 2024 Apr; 9(10). PMID: 38652538
Manganese is an essential yet potentially toxic metal. Initially reported in 2012, mutations in SLC30A10 are the first known inherited cause of manganese excess. SLC30A10 is an apical membrane protein...
9.
Guo S, Fu L, Yin C, Shao W, Sun Q, Chen L, et al.
Inflammation . 2024 Apr; 47(6):1918-1935. PMID: 38630168
Periodontal disease is the pathological outcome of the overwhelming inflammation in periodontal tissue. Cellular senescence has been associated with chronic inflammation in several diseases. However, the role of cellular senescence...
10.
Li J, Fu L, Lu Q, Guo S, Chen S, Xia T, et al.
Tissue Cell . 2024 Mar; 88:102358. PMID: 38537379
Objective: With the growing interest in the role of fibroblasts in osteogenesis, this study presents a comparative evaluation of the osteogenic potential of fibroblasts derived from three distinct sources: human...