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Melanie Greter

Explore the profile of Melanie Greter including associated specialties, affiliations and a list of published articles. Areas
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Articles 78
Citations 13190
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Recent Articles
1.
Van Hove H, De Feo D, Greter M, Becher B
Annu Rev Immunol . 2025 Mar; PMID: 40036702
The central nervous system (CNS) has a unique set of macrophages that seed the tissue early during embryonic development. Microglia reside in the parenchyma, and border-associated macrophages are present in...
2.
Lehtonen H, Jokela H, Hofmann J, Tola L, Mehmood A, Ginhoux F, et al.
Cell Rep . 2025 Jan; 44(2):115227. PMID: 39841599
The pituitary gland is the central endocrine regulatory organ producing and releasing hormones that coordinate major body functions. The physical location of the pituitary gland at the base of the...
3.
Wu Y, Korobeynyk V, Zamboni M, Waern F, Cole J, Mundt S, et al.
Nat Neurosci . 2025 Jan; 28(2):415-430. PMID: 39762661
The mammalian dentate gyrus (DG) is involved in certain forms of learning and memory, and DG dysfunction has been implicated in age-related diseases. Although neurogenic potential is maintained throughout life...
4.
Bijnen M, Sridhar S, Keller A, Greter M
Trends Immunol . 2024 Dec; 46(1):46-60. PMID: 39732528
Diverse macrophage populations inhabit the rodent and human central nervous system (CNS), including microglia in the parenchyma and border-associated macrophages (BAMs) in the meninges, choroid plexus, and perivascular spaces. These...
5.
Sparano C, Solis-Sayago D, Zangger N, Rindlisbacher L, Van Hove H, Vermeer M, et al.
J Exp Med . 2024 Dec; 222(3). PMID: 39692745
Group 1 innate lymphoid cells (ILCs) encompass NK cells and ILC1s, which have non-redundant roles in host protection against pathogens and cancer. Despite their circulating nature, NK cells can establish...
6.
Fan Z, Karakone M, Nagarajan S, Nagy N, Mildenberger W, Petrova E, et al.
Cell Rep . 2024 Jun; 43(7):114395. PMID: 38941187
Macrophages play crucial roles in organ-specific functions and homeostasis. In the adrenal gland, macrophages closely associate with sinusoidal capillaries in the aldosterone-producing zona glomerulosa. We demonstrate that macrophages preserve capillary...
7.
Vinnakota J, Adams R, Athanassopoulos D, Schmidt D, Biavasco F, Zahringer A, et al.
Sci Transl Med . 2024 Jun; 16(751):eadj9672. PMID: 38865481
Cancer treatment with anti-PD-1 immunotherapy can cause central nervous system immune-related adverse events (CNS-irAEs). The role of microglia in anti-PD-1 immunotherapy-induced CNS-irAEs is unclear. We found that anti-PD-1 treatment of...
8.
Bosch A, Keller L, Steiger L, Rohm T, Wiedemann S, Low A, et al.
Diabetologia . 2023 Oct; 66(12):2292-2306. PMID: 37792013
Aims/hypothesis: Colony stimulating factor 1 (CSF1) promotes the proliferation, differentiation and survival of macrophages, which have been implicated in both beneficial and detrimental effects on glucose metabolism. However, the physiological...
9.
Andreadou M, Ingelfinger F, De Feo D, Cramer T, Tuzlak S, Friebel E, et al.
Nat Neurosci . 2023 Sep; 26(10):1701-1712. PMID: 37749256
Interleukin-12 (IL-12) is a potent driver of type 1 immunity. Paradoxically, in autoimmune conditions, including of the CNS, IL-12 reduces inflammation. The underlying mechanism behind these opposing properties and the...
10.
Maheshwari U, Mateos J, Weber-Stadlbauer U, Ni R, Tamatey V, Sridhar S, et al.
Brain Pathol . 2023 Jul; 33(6):e13189. PMID: 37505935
Calcification of the cerebral microvessels in the basal ganglia in the absence of systemic calcium and phosphate imbalance is a hallmark of primary familial brain calcification (PFBC), a rare neurodegenerative...