Melania Capitani
Overview
Explore the profile of Melania Capitani including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
17
Citations
654
Followers
0
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Recent Articles
1.
Capitani M, Al-Shaibi A, Pandey S, Gartner L, Taylor H, Hubrack S, et al.
J Allergy Clin Immunol
. 2022 Dec;
151(3):783-790.e5.
PMID: 36462956
Background: Toll-like receptors (TLRs) mediate functions for host defense and inflammatory responses. TLR4 recognizes LPS, a component of gram-negative bacteria as well as host-derived endogenous ligands such as S100A8 and...
2.
Aschenbrenner D, Ye Z, Zhou Y, Hu W, Brooks I, Williams I, et al.
J Clin Immunol
. 2022 Nov;
43(2):495-511.
PMID: 36370291
Balancing natural selection is a process by which genetic variants arise in populations that are beneficial to heterozygous carriers, but pathogenic when homozygous. We systematically investigated the prevalence, structural, and...
3.
Cavounidis A, Pandey S, Capitani M, Friedrich M, Cross A, Gartner L, et al.
Mucosal Immunol
. 2022 Oct;
15(6):1431-1446.
PMID: 36302964
Hermansky-Pudlak syndrome (HPS) types 1 and 4 are caused by defective vesicle trafficking. The mechanism for Crohn's disease-like inflammation, lung fibrosis, and macrophage lipid accumulation in these patients remains enigmatic....
4.
Wang L, Aschenbrenner D, Zeng Z, Cao X, Mayr D, Mehta M, et al.
Nat Genet
. 2022 Jan;
54(2):213.
PMID: 34987219
No abstract available.
5.
Bolton C, Smillie C, Pandey S, Elmentaite R, Wei G, Argmann C, et al.
Gastroenterology
. 2021 Nov;
162(3):859-876.
PMID: 34780721
Background & Aims: Monogenic forms of inflammatory bowel disease (IBD) illustrate the essential roles of individual genes in pathways and networks safeguarding immune tolerance and gut homeostasis. Methods: To build...
6.
Wang L, Aschenbrenner D, Zeng Z, Cao X, Mayr D, Mehta M, et al.
Nat Genet
. 2021 Mar;
53(4):500-510.
PMID: 33782605
Spleen tyrosine kinase (SYK) is a critical immune signaling molecule and therapeutic target. We identified damaging monoallelic SYK variants in six patients with immune deficiency, multi-organ inflammatory disease such as...
7.
Mukhopadhyay S, Heinz E, Porreca I, Alasoo K, Yeung A, Yang H, et al.
J Exp Med
. 2019 Dec;
217(2).
PMID: 31819956
Loss of IL-10 signaling in macrophages (Mφs) leads to inflammatory bowel disease (IBD). Induced pluripotent stem cells (iPSCs) were generated from an infantile-onset IBD patient lacking a functional IL10RB gene....
8.
Hong Y, Capitani M, Murphy C, Pandey S, Cavounidis A, Takeshita H, et al.
J Allergy Clin Immunol
. 2019 Nov;
145(2):701-705.e8.
PMID: 31775019
No abstract available.
9.
Schulthess J, Pandey S, Capitani M, Rue-Albrecht K, Arnold I, Franchini F, et al.
Immunity
. 2019 Jan;
50(2):432-445.e7.
PMID: 30683619
Host microbial cross-talk is essential to maintain intestinal homeostasis. However, maladaptation of this response through microbial dysbiosis or defective host defense toward invasive intestinal bacteria can result in chronic inflammation....
10.
Bordoni L, Fedeli D, Nasuti C, Capitani M, Fiorini D, Gabbianelli R
Comp Biochem Physiol C Toxicol Pharmacol
. 2017 Sep;
201:51-57.
PMID: 28943456
The mechanisms associated to the development of neurodegeneration due to pesticide exposure are not clear yet. In this study we evaluated how permethrin pesticide (PERM) can influence the Nurr1 gene...