Meichen Dong
Overview
Explore the profile of Meichen Dong including associated specialties, affiliations and a list of published articles.
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Articles
18
Citations
473
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Recent Articles
11.
Li Z, Wang D, Lu J, Huang B, Wang Y, Dong M, et al.
Cell Death Differ
. 2020 Sep;
27(12):3226-3242.
PMID: 32895488
Enhancer of zeste homolog 2 (EZH2), a key histone methyltransferase and EMT inducer, is overexpressed in diverse carcinomas, including breast cancer. However, the molecular mechanisms of EZH2 dysregulation in cancers...
12.
Dong M, Thennavan A, Urrutia E, Li Y, Perou C, Zou F, et al.
Brief Bioinform
. 2020 Jan;
22(1):416-427.
PMID: 31925417
Recent advances in single-cell RNA sequencing (scRNA-seq) enable characterization of transcriptomic profiles with single-cell resolution and circumvent averaging artifacts associated with traditional bulk RNA sequencing (RNA-seq) data. Here, we propose...
13.
Dong M, Jiang Y
Methods Mol Biol
. 2019 Feb;
1935:155-174.
PMID: 30758826
Allele-specific expression is traditionally studied by bulk RNA sequencing, which measures average gene expression across cells. Single-cell RNA sequencing (scRNA-seq) allows the comparison of expression distribution between the two alleles...
14.
Li Z, Dong M, Fan D, Hou P, Li H, Liu L, et al.
Oncotarget
. 2017 Oct;
8(40):67329-67343.
PMID: 28978036
Epithelial to mesenchymal transition (EMT) is a progression of cellular plasticity critical for development, differentiation, cancer cells migration and tumor metastasis. As a well-studied factor, TGF-β participates in EMT and...
15.
Li Z, Hou P, Fan D, Dong M, Ma M, Li H, et al.
Cell Death Differ
. 2016 Oct;
24(1):59-71.
PMID: 27716745
EZH2 (the Enhancer of Zeste Homolog 2), as a key epigenetic regulator and EMT inducer, participates in a variety of cancer metastasis. EZH2 stability is regulated by several types of...
16.
Yang X, Ouyang H, Chen F, Ma T, Dong M, Wang F, et al.
Clin Exp Pharmacol Physiol
. 2014 Aug;
41(12):950-5.
PMID: 25115523
The 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR) pathway is an important metabolic route that is present in almost every organism. However, whether HMGCR affects the expression of interferon (IFN)-responsive genes is unclear....
17.
Chen F, Yang X, Pang D, Peng Z, Dong M, Liu X, et al.
Int J Biol Macromol
. 2014 Apr;
67:289-94.
PMID: 24690536
Capsid protein (Cap) of porcine circovirus 2 (PCV2) contained critical epitopes for inducing a protective immune response. Here, different fragments of PCV2 Cap protein were cloned, expressed, purified and used...
18.
HMG-CoA reductase is negatively associated with PCV2 infection and PCV2-induced apoptotic cell death
Yang X, Ouyang H, Chen F, Pang D, Dong M, Yang S, et al.
J Gen Virol
. 2014 Mar;
95(Pt 6):1330-1337.
PMID: 24643880
We examined the role of HMG-CoA reductase (HMGCR) during porcine circovirus 2 (PCV2) infection. The results demonstrated that levels of endogenous HMGCR were not significantly different in PCV2-infected cells and...