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Mei-Rong Ke

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Articles 35
Citations 287
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Recent Articles
1.
Liu H, Li Z, Zhang X, Xu Y, Tang G, Wang Z, et al.
Nat Commun . 2025 Jan; 16(1):326. PMID: 39747902
Photodynamic immunotherapy (PIT) has emerged as a promising approach for efficient eradication of primary tumors and inhibition of tumor metastasis. However, most of photosensitizers (PSs) for PIT exhibit notable oxygen...
2.
Zhang L, Que R, Ke T, Wang C, Xie W, Sun H, et al.
J Photochem Photobiol B . 2024 Nov; 261:113067. PMID: 39577037
The development of a simple drug formulation capable of achieving both activatable type I photoreaction and tumor-responsive release of immunomodulator is crucial for advancing photodynamic immunotherapy (PDIT). Herein, we present...
3.
Ke M, Chen Z, Shi J, Wei Y, Liu H, Huang S, et al.
Chem Commun (Camb) . 2023 Jul; 59(65):9832-9835. PMID: 37505224
Unlike traditional methods of modifying phthalocyanines (Pcs), we herein report a smart and visible way to switch the aromaticity of silicon(IV) phthalocyanines a reversible nucleophilic addition reaction of the Pc...
4.
Ma X, Zhang W, Que R, Wang C, Shang W, Zhu Y, et al.
Chempluschem . 2022 Oct; 87(10):e202200113. PMID: 36220346
This work reports the development of a multifunctional thermosensitive liposomal nanoplatform (PcS@Lip-FA) based on a metal-free phthalocyanine modified with tetra-sulfonates (PcPS), which exhibited photodynamic and photothermal activities simultaneously. Upon irradiation...
5.
Liu H, Lv L, Wen H, Zhao D, Wu J, Ke M, et al.
ACS Appl Mater Interfaces . 2022 Jun; 14(25):28581-28590. PMID: 35709499
Phototherapy for non-invasive cancer treatment has been extensively studied. An urgent challenge in phototherapy application is to fabricate appropriate targeted agents to achieve efficient therapeutic effect. Herein, a molecular and...
6.
Zhao P, Ma S, Hu J, Zheng B, Ke M, Huang J
ACS Appl Bio Mater . 2022 Jan; 3(11):7876-7885. PMID: 35019528
Thermodynamic therapy (TDT), one that uses heat to activate thermosensitizers and produce reactive oxygen species (ROS), has recently emerged as an attractive approach for cancer therapy. However, the development of...
7.
Zhao P, Wu Y, Li X, Feng L, Zhang L, Zheng B, et al.
Angew Chem Int Ed Engl . 2021 Nov; 61(5):e202113506. PMID: 34761489
The clinical prospect of sonodynamic therapy (SDT) has not been fully realized due to the scarcity of efficient sonosensitizers. Herein, we designed phthalocyanine-artesunate conjugates (e.g. ZnPcT A), which could generate...
8.
Zheng B, Huang Z, Lv L, Lan W, Hu J, Li X, et al.
J Mater Chem B . 2021 Mar; 9(12):2845-2853. PMID: 33704321
Photothermal therapy (PTT) is a promising strategy for cancer treatment. However, the development of highly efficient photothermal agents with excellent biosafety, particularly with low liver retention, is very meaningful for...
9.
Lin A, Chen J, Hong J, Zhao Y, Zheng B, Ke M, et al.
J Inorg Biochem . 2021 Feb; 217:111371. PMID: 33588279
To develop highly efficient photosensitizers for photodynamic therapy, herein a zinc(II) phthalocyanine-folate conjugate (PcN-FA) used to construct an activatable nanophotosensitizer (NanoPcN-FA) through a facile self-assembly. The self-assembled nanophotosensitizer (NanoPcN) without...
10.
Zheng B, Li S, Huang Z, Zhang L, Liu H, Zheng B, et al.
J Photochem Photobiol B . 2020 Nov; 213:112086. PMID: 33232881
With a view to developing highly efficient photosensitizers for both antitumor and antimicrobial photodynamic therapies, herein, we reported a super cationic zinc(II) phthalocyanine (Pc4), which was prepared through the quaternization...