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Mehmet Hakan Guney

Explore the profile of Mehmet Hakan Guney including associated specialties, affiliations and a list of published articles. Areas
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Articles 4
Citations 86
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Recent Articles
1.
Guney M, Nagalekshmi K, McCauley S, Carbone C, Aydemir O, Luban J
Proc Natl Acad Sci U S A . 2024 Jul; 121(29):e2404349121. PMID: 38985764
Intron-containing RNA expressed from the HIV-1 provirus activates type 1 interferon in primary human blood cells, including CD4 T cells, macrophages, and dendritic cells. To identify the innate immune receptor...
2.
Guney M, Nagalekshmi K, McCauley S, Carbone C, Aydemir O, Luban J
bioRxiv . 2023 Nov; PMID: 38014177
Antiretroviral therapy (ART) suppresses HIV-1 viremia and prevents progression to AIDS. Nonetheless, chronic inflammation is a common problem for people living with HIV-1 on ART. One possible cause of inflammation...
3.
Xue G, Yu H, Buffone C, Huang S, Lee K, Goh S, et al.
Nat Commun . 2023 Jun; 14(1):3782. PMID: 37355754
The movement of viruses and other large macromolecular cargo through nuclear pore complexes (NPCs) is poorly understood. The human immunodeficiency virus type 1 (HIV-1) provides an attractive model to interrogate...
4.
Yurkovetskiy L, Guney M, Kim K, Goh S, McCauley S, Dauphin A, et al.
Nat Microbiol . 2018 Oct; 3(12):1354-1361. PMID: 30297740
Host factors that silence provirus transcription in CD4 memory T cells help HIV-1 escape eradication by the host immune system and by antiviral drugs. These same factors, however, must be...