Karthika Nagalekshmi
Overview
Explore the profile of Karthika Nagalekshmi including associated specialties, affiliations and a list of published articles.
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4
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5
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Recent Articles
1.
Rodriguez T, Yurkovetskiy L, Nagalekshmi K, Lam C, Jazbec E, Maitland S, et al.
bioRxiv
. 2024 Jul;
PMID: 39026796
An obligate step in the life cycle of HIV-1 and other retroviruses is the establishment of the provirus in target cell chromosomes. Transcriptional regulation of proviruses is complex, and understanding...
2.
Guney M, Nagalekshmi K, McCauley S, Carbone C, Aydemir O, Luban J
Proc Natl Acad Sci U S A
. 2024 Jul;
121(29):e2404349121.
PMID: 38985764
Intron-containing RNA expressed from the HIV-1 provirus activates type 1 interferon in primary human blood cells, including CD4 T cells, macrophages, and dendritic cells. To identify the innate immune receptor...
3.
Guney M, Nagalekshmi K, McCauley S, Carbone C, Aydemir O, Luban J
bioRxiv
. 2023 Nov;
PMID: 38014177
Antiretroviral therapy (ART) suppresses HIV-1 viremia and prevents progression to AIDS. Nonetheless, chronic inflammation is a common problem for people living with HIV-1 on ART. One possible cause of inflammation...
4.
Kumar D, Gauthami S, Uma M, Nagalekshmi K, Rao P, Basu A, et al.
Viral Immunol
. 2018 Aug;
31(7):500-512.
PMID: 30095362
Ebolavirus (EBOV) is the etiology of Ebola hemorrhagic fever (EHF). A major EHF outbreak in 2014-2015 in West Africa claimed >11,000 lives. A licensed vaccine is not available for EHF,...