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Mehdi Shafa

Explore the profile of Mehdi Shafa including associated specialties, affiliations and a list of published articles. Areas
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Articles 13
Citations 193
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Recent Articles
1.
Babu S, Duvvuru H, Baker J, Switalski S, Shafa M, Panchalingam K, et al.
Biotechnol Rep (Amst) . 2023 Feb; 37:e00784. PMID: 36818379
Human induced pluripotent stem cells (iPSC) have demonstrated massive potentials for use in regenerative and personalized medicine due to their ability to expand in culture and differentiate into specialized cells...
2.
Vazifehmand R, Ali D, Othman Z, Chau D, Stanslas J, Shafa M, et al.
J Neurovirol . 2022 Aug; 28(4-6):566-582. PMID: 35951174
Glioblastoma multiforme is the most aggressive astrocytes brain tumor. Glioblastoma cancer stem cells and hypoxia conditions are well-known major obstacles in treatment. Studies have revealed that non-coding RNAs serve a...
3.
Dashtban M, Panchalingam K, Shafa M, Ahmadian Baghbaderani B
Methods Mol Biol . 2020 May; 2286:179-198. PMID: 32430594
The development of reprogramming technology to generate human induced pluripotent stem cells (iPSCs) has tremendously influenced the field of regenerative medicine and clinical therapeutics where curative cell replacement therapies can...
4.
Shafa M, Walsh T, Panchalingam K, Richardson T, Menendez L, Tian X, et al.
Int J Mol Sci . 2019 Dec; 21(1). PMID: 31877913
The clinical effectiveness of human induced pluripotent stem cells (iPSCs) is highly dependent on a few key quality characteristics including the generation of high quality cell bank, long-term genomic stability,...
5.
Shafa M, Panchalingam K, Walsh T, Richardson T, Ahmadian Baghbaderani B
Biotechnol Bioeng . 2019 Sep; 116(12):3228-3241. PMID: 31483482
Induced pluripotent stem cells (iPSCs) hold great potential to generate novel, curative cell therapy products. However, current methods to generate these novel therapies lack scalability, are labor-intensive, require a large...
6.
Shafa M, Yang F, Fellner T, Rao M, Ahmadian Baghbaderani B
Front Med (Lausanne) . 2018 Mar; 5:69. PMID: 29600249
The discovery of reprogramming and generation of human-induced pluripotent stem cells (iPSCs) has revolutionized the field of regenerative medicine and opened new opportunities in cell replacement therapies. While generation of...
7.
Shafa M, Ionescu L, Vadivel A, Collins J, Xu L, Zhong S, et al.
Cytotherapy . 2017 Oct; 20(1):108-125. PMID: 29056548
Background Aims: Bronchopulmonary dysplasia (BPD), a chronic lung disease characterized by disrupted lung growth, is the most common complication in extreme premature infants. BPD leads to persistent pulmonary disease later...
8.
Shafa M, Day B, Yamashita A, Meng G, Liu S, Krawetz R, et al.
Nat Methods . 2012 Apr; 9(5):465-6. PMID: 22484846
Induced pluripotent stem cells (iPSCs) are typically derived in adherent culture. Here we report fast and efficient derivation of mouse iPSCs in stirred suspension bioreactors, with and without the use...
9.
Shafa M, Krawetz R, Zhang Y, Rattner J, Godollei A, Duff H, et al.
BMC Cell Biol . 2011 Dec; 12:53. PMID: 22168552
Background: Embryonic stem cells (ESCs) can proliferate endlessly and are able to differentiate into all cell lineages that make up the adult organism. Under particular in vitro culture conditions, ESCs...
10.
Shafa M, Sjonnesen K, Yamashita A, Liu S, Michalak M, Kallos M, et al.
J Tissue Eng Regen Med . 2011 Jul; 6(6):462-72. PMID: 21761573
Induced pluripotent stem cells (iPSCs) can provide an important source of cells for the next-generation of cell therapies in regenerative medicine, in part due to their similarity to embryonic stem...