Megumi Yoshioka
Overview
Explore the profile of Megumi Yoshioka including associated specialties, affiliations and a list of published articles.
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Articles
14
Citations
100
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0
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Recent Articles
1.
Jounai N, Yoshioka M, Tozuka M, Inoue K, Oka T, Miyaji K, et al.
EBioMedicine
. 2017 Jan;
16:124-135.
PMID: 28111238
Respiratory syncytial virus (RSV) is one of the most prevalent causative agents of lower respiratory tract infections worldwide, especially in infants around 3 to 4months old. Infants at such a...
2.
Kurosawa N, Wakata Y, Inobe T, Kitamura H, Yoshioka M, Matsuzawa S, et al.
Sci Rep
. 2016 Apr;
6:25174.
PMID: 27125496
Threonine phosphorylation accounts for 10% of all phosphorylation sites compared with 0.05% for tyrosine and 90% for serine. Although monoclonal antibody generation for phospho-serine and -tyrosine proteins is progressing, there...
3.
Hayashi S, Yoshioka M, Matsui T, Kojima K, Kato M, Kanamaru K, et al.
FEBS Open Bio
. 2014 Feb;
4:90-5.
PMID: 24490133
Sensor histidine kinases (HKs) are important factors that control cellular growth in response to environmental conditions. The expression of 15 HKs from Aspergillus nidulans was analyzed by quantitative real-time PCR...
4.
Miyamori T, Sato M, Nishi T, Yamagishi T, Hattori Y, Ishii N, et al.
Gan To Kagaku Ryoho
. 2012 Dec;
39 Suppl 1:3-5.
PMID: 23268883
Quantitative and qualitative analyses of a caring family are needed to improve home care. We propose a three-dimensional quantitative evaluation of family functioning. The first dimension is food, clothing, and...
5.
Kurosawa N, Yoshioka M, Fujimoto R, Yamagishi F, Isobe M
BMC Biol
. 2012 Sep;
10:80.
PMID: 23017270
Background: Although a variety of animals have been used to produce polyclonal antibodies against antigens, the production of antigen-specific monoclonal antibodies from animals remains challenging. Results: We propose a simple...
6.
Yoshioka M, Kurosawa N, Isobe M
BMC Biotechnol
. 2011 Jul;
11:75.
PMID: 21774833
Background: During the development of a therapeutic antibody, large numbers of monoclonal antibodies are required to screen for those that are best suited for the desired activity. Although the single...
7.
Kurosawa N, Yoshioka M, Isobe M
BMC Biotechnol
. 2011 Apr;
11:39.
PMID: 21486488
Background: Molecular cloning of functional immunoglobulin genes from single plasma cells is one of the most promising technologies for the rapid development of monoclonal antibody drugs. However, the proper insertion...
8.
Yamashiro D, Yoshioka M, Ashiuchi M
Biotechnol Bioeng
. 2010 Sep;
108(1):226-30.
PMID: 20812257
Poly-γ-glutamate (PGA) is a versatile nylon-like material, and enhanced production of PGA is required for various bio-industrial applications. In this study, we first examined the effects of available sugars on...
9.
Katritzky A, Yoshioka M, Narindoshvili T, Chung A, Johnson J
Org Biomol Chem
. 2008 Nov;
6(24):4582-6.
PMID: 19039367
N(alpha)-Fmoc-N(epsilon)-[(7-methoxycoumarin-4-yl)acetyl]-L-lysine (N(alpha)-Fmoc-L-Lys(Mca)-OH) 3 is conveniently prepared by benzotriazole methodology (52% over two steps). N-Acylbenzotriazoles Mca-Bt 2, N(alpha)-Fmoc-L-Lys(Mca)-Bt 4, coumarin-3-ylcarbonyl (Cc)-Bt 5, N(alpha)-Fmoc-L-Lys(Cc)-Bt 7 and N(alpha)-(Cc)-L-Lys(Fmoc)-Bt 9 enable the efficient microwave...
10.
Katritzky A, Yoshioka M, Narindoshvili T, Chung A, Khashab N
Chem Biol Drug Des
. 2008 Aug;
72(3):182-8.
PMID: 18715231
N-Fmoc-protected(alpha-aminoacyl)benzotriazoles 1a-d readily afford chiral N-Fmoc-protected-alpha-dipeptides 2a-f (77-89%). Compounds 2a-f are further converted into N-Fmoc-protected(alpha-dipeptidoyl)benzotriazoles 3a-f (71% average yield). Under mild microwave irradiation, 3a-f are used in solid-phase peptide segment...