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Megumi Kawai

Explore the profile of Megumi Kawai including associated specialties, affiliations and a list of published articles. Areas
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Articles 19
Citations 156
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Recent Articles
1.
Saito A, Sakai K, Kawai M, Lyu L, Kameda K, Kudo H, et al.
Front Physiol . 2025 Jan; 15:1511443. PMID: 39877661
Measuring the heart rate of sea turtles is important for understanding their physiological adaptations to the environment. Non-invasive methods to measure the electrocardiogram (ECG) of sea turtles have been developed...
2.
Saito A, Kinoshita C, Kawai M, Fukuoka T, Sato K, Sakamoto K
J Exp Biol . 2022 Apr; 225(9). PMID: 35441228
Diving bradycardia is a reduction in the heart rate mediated by the parasympathetic system during diving. Although diving bradycardia is pronounced in aquatic mammals and birds, the existence of this...
3.
Kinoshita C, Saito A, Kawai M, Sato K, Sakamoto K
Front Physiol . 2022 Mar; 13:811947. PMID: 35250617
Heart rate measurement is an essential method for evaluating the physiological status of air-breathing diving animals. However, owing to technical difficulties, many marine animals require an invasive approach to record...
4.
Oki H, Masuda T, Hayashi-Miyamoto M, Kawai M, Ito M, Madarame H, et al.
J Gen Virol . 2022 Feb; 103(2). PMID: 35175914
Rotavirus C (RVC) is a major cause of diarrhoea in swine, cattle, and humans worldwide. RVC exhibits sequence diversity in all 11 genes, especially in VP4 and VP7, and all...
5.
Oba M, Sakaguchi S, Wu H, Fujioka Y, Takemae H, Oki H, et al.
J Gen Virol . 2022 Feb; 103(2). PMID: 35138239
A novel picornavirus was isolated from the faeces of a diarrhoeic cow using MA-104 cells at the third blind passage. This virus, named Den1/2021/JPN, was completely sequenced using total RNA...
6.
Ishimoto K, Hayase A, Kumagai F, Kawai M, Okuno H, Hino N, et al.
Biochem Biophys Res Commun . 2017 May; 488(1):159-164. PMID: 28483528
Lipin-1 has dual functions in the regulation of lipid and energy metabolism according to its subcellular localization, which is tightly controlled. However, it is unclear how Lipin-1 degradation is regulated....
7.
Chen B, Kawai M, Wu-Wong J
Bioorg Med Chem Lett . 2013 Sep; 23(21):5949-52. PMID: 24035340
We have synthesized a novel vitamin D receptor agonist VS-105 ((1R,3R)-5-((E)-2-((3αS,7αS)-1-((R)-1-((S)-3-hydroxy-2,3-dimethylbutoxy)ethyl)-7α-methyldihydro-1H-inden-4(2H,5H,6H,7H,7αH)-ylidene)ethylidene)-2-methylenecyclohexane-1,3-diol). Preparation of a-ring phenylphosphine oxide 11, followed by Wittig-Horner coupling of 11 with the protected 25-hydroxy Grundmann's ketone 22...
8.
Nagai M, Hori N, Miyamoto M, Sakaguchi M, Hayakawa Y, Kawai M, et al.
Anim Sci J . 2013 Apr; 84(6):461-5. PMID: 23607693
To improve embryo development in bovine separated blastomeres, we evaluated applicability of co-culture with intact embryos. The morphological quality of blastocysts derived from separated blastomeres and rate of blastocyst formation...
9.
Wu-Wong J, Kawai M, Chen Y, Wessale J, Huang C, Wu M, et al.
Am J Nephrol . 2013 Apr; 37(4):310-9. PMID: 23548814
Background/aims: Vitamin D receptor modulators (VDRMs) are indicated for secondary hyperparathyroidism in chronic kidney disease (CKD). Clinical observations demonstrate that VDRM therapy provides cardiovascular (CV) benefit in CKD. Current on-market...
10.
Wu-Wong J, Kawai M, Chen Y, Nakane M
Br J Pharmacol . 2011 May; 164(2b):551-60. PMID: 21557735
Background And Purpose: Vitamin D receptor (VDR) modulators (VDRMs) such as calcitriol, paricalcitol and doxercalciferol are commonly used to manage hyperparathyroidism secondary to chronic kidney disease (CKD). CKD patients experience...