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» Authors » Meghan C OMeara

Meghan C OMeara

Explore the profile of Meghan C OMeara including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 7
Citations 203
Followers 0
Related Specialties
Physiology
Endocrinology
Cell Biology
Top 10 Co-Authors
Paul J Rozance
Laura D Brown
Stephanie R Thorn
William W Hay Jr
Jinny R Lavezzi
Monika M Gadhia
Anne M Maliszewski
Jason Gien
Steven H Abman
Gates Roe
Published In
Am J Physiol Endocrinol Metab
Am J Physiol Regul Integr Comp Physiol
Physiol Rep
Am J Physiol Lung Cell Mol Physiol
Affiliations
Soon will be listed here.
Recent Articles
1.
A physiological increase in insulin suppresses muscle-specific ubiquitin ligase gene activation in fetal sheep with sustained hypoglycemia
Brown L, Thorn S, OMeara M, Lavezzi J, Rozance P
Physiol Rep . 2014 Jun; 2(6). PMID: 24944291
Decreased glucose transfer to the fetus is characteristic of pregnancies complicated by maternal under nutrition and placental insufficiency. Chronic experimental restriction of glucose transfer to the sheep fetus for the...
2.
Increased amino acid supply potentiates glucose-stimulated insulin secretion but does not increase β-cell mass in fetal sheep
Gadhia M, Maliszewski A, OMeara M, Thorn S, Lavezzi J, Limesand S, et al.
Am J Physiol Endocrinol Metab . 2012 Dec; 304(4):E352-62. PMID: 23211516
Amino acids and glucose acutely stimulate fetal insulin secretion. In isolated adult pancreatic islets, amino acids potentiate glucose-stimulated insulin secretion (GSIS), but whether amino acids have this same effect in...
3.
Increased fetal insulin concentrations for one week fail to improve insulin secretion or β-cell mass in fetal sheep with chronically reduced glucose supply
Lavezzi J, Thorn S, OMeara M, LoTurco D, Brown L, Hay Jr W, et al.
Am J Physiol Regul Integr Comp Physiol . 2012 Nov; 304(1):R50-8. PMID: 23135788
Maternal undernutrition during pregnancy and placental insufficiency are characterized by impaired development of fetal pancreatic β-cells. Prolonged reduced glucose supply to the fetus is a feature of both. It is...
4.
A physiological increase in insulin suppresses gluconeogenic gene activation in fetal sheep with sustained hypoglycemia
Thorn S, Sekar S, Lavezzi J, OMeara M, Brown L, Hay Jr W, et al.
Am J Physiol Regul Integr Comp Physiol . 2012 Aug; 303(8):R861-9. PMID: 22933022
Reduced maternal glucose supply to the fetus and resulting fetal hypoglycemia and hypoinsulinemia activate fetal glucose production as a means to maintain cellular glucose uptake. However, this early activation of...
5.
Prolonged infusion of amino acids increases leucine oxidation in fetal sheep
Maliszewski A, Gadhia M, OMeara M, Thorn S, Rozance P, Brown L
Am J Physiol Endocrinol Metab . 2012 Mar; 302(12):E1483-92. PMID: 22454287
Maternal high-protein supplements designed to increase birth weight have not been successful. We recently showed that maternal amino acid infusion into pregnant sheep resulted in competitive inhibition of amino acid...
6.
Intrauterine growth restriction decreases pulmonary alveolar and vessel growth and causes pulmonary artery endothelial cell dysfunction in vitro in fetal sheep
Rozance P, Seedorf G, Brown A, Roe G, OMeara M, Gien J, et al.
Am J Physiol Lung Cell Mol Physiol . 2011 Aug; 301(6):L860-71. PMID: 21873446
Intrauterine growth restriction (IUGR) increases the risk for bronchopulmonary dysplasia (BPD). Abnormal lung structure has been noted in animal models of IUGR, but whether IUGR adversely impacts fetal pulmonary vascular...
7.
Prolonged maternal amino acid infusion in late-gestation pregnant sheep increases fetal amino acid oxidation
Rozance P, Crispo M, Barry J, OMeara M, Frost M, Hansen K, et al.
Am J Physiol Endocrinol Metab . 2009 Jul; 297(3):E638-46. PMID: 19602583
Protein supplementation during human pregnancy does not improve fetal growth and may increase small-for-gestational-age birth rates and mortality. To define possible mechanisms, sheep with twin pregnancies were infused with amino...