Meg L Donovan
Overview
Explore the profile of Meg L Donovan including associated specialties, affiliations and a list of published articles.
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6
Citations
74
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Recent Articles
1.
Naei V, Tubelleza R, Monkman J, Sadeghirad H, Donovan M, Blick T, et al.
J Transl Med
. 2025 Feb;
23(1):177.
PMID: 39939997
Background: Mucosal head and neck squamous cell carcinoma (HNSCC) is often diagnosed at an advanced stage, where the prognosis is poor due to the high rates of recurrence and metastasis....
2.
Kulasinghe A, Berrell N, Donovan M, Nilges B
Methods Mol Biol
. 2025 Feb;
2880:101-146.
PMID: 39900756
Traditional tissue profiling approaches have evolved from bulk studies to single-cell analysis over the last decade; however, the spatial context in tissues and microenvironments has always been lost. Over the...
3.
Miranda-Hernandez S, Kumar M, Henderson A, Graham E, Tan X, Taylor J, et al.
bioRxiv
. 2025 Feb;
PMID: 39896630
It is estimated that two billion people are latently infected with ( ), the causative agent of tuberculosis (TB). Latent infection (LTBI) can occur in multiple organs, including the lymphatics....
4.
Sadeghirad H, Monkman J, Tan C, Liu N, Yunis J, Donovan M, et al.
J Transl Med
. 2024 Jul;
22(1):677.
PMID: 39049036
Background: Recurrent/metastatic head and neck squamous cell carcinoma (R/M HNSCC) generally has a poor prognosis for patients with limited treatment options. While incorporating immune checkpoint inhibitors (ICIs) has now become...
5.
Donovan M, Jhaveri N, Ma N, Ben Cheikh B, DeRosa J, Mihani R, et al.
STAR Protoc
. 2024 Jul;
5(3):103226.
PMID: 39031553
Single-cell spatial analysis of proteins is rapidly becoming increasingly important in revealing biological insights. Here, we present a protocol for automated high-plex multi-slide immunofluorescence staining and imaging of human head...
6.
Donovan M, Bielefeldt-Ohmann H, Rollo R, McPherson S, Schultz T, Mori G, et al.
Immunology
. 2022 Nov;
169(1):13-26.
PMID: 36370035
Granulomas are key histopathological features of Mycobacterium tuberculosis (Mtb) infection, with complex roles in pathogen control and dissemination. Thus, understanding drivers and regulators of granuloma formation is important for improving...
7.
Dominguez Cadena L, Schultz T, Zamoshnikova A, Donovan M, Mathmann C, Yu C, et al.
Immunol Cell Biol
. 2021 Sep;
99(10):1067-1076.
PMID: 34555867
The proinflammatory cytokine tumor necrosis factor (TNF) plays a central role in the host control of mycobacterial infections. Expression and release of TNF are tightly regulated, yet the molecular mechanisms...
8.
Sinha R, Ngo M, Bartlett S, Bielefeldt-Ohmann H, Keshvari S, Hasnain S, et al.
Front Cell Infect Microbiol
. 2021 Jul;
11:691823.
PMID: 34295838
Type 2 diabetes (T2D) is a well-known risk factor for tuberculosis (TB), but little is known about pre-diabetes and the relative contribution of impaired glucose tolerance obesity towards susceptibility to...
9.
Donovan M, Schultz T, Duke T, Blumenthal A
Front Immunol
. 2017 Dec;
8:1633.
PMID: 29230217
Tuberculosis (TB) remains a major global health threat. Urgent needs in the fight against TB include improved and innovative treatment options for drug-sensitive and -resistant TB as well as reliable...