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Mayssa H Mokalled

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Articles 25
Citations 712
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Recent Articles
1.
Reyes C, Mokalled M
Adv Neurobiol . 2024 Aug; 39:213-231. PMID: 39190077
Spinal cord injuries cause irreversible loss of sensory and motor functions. In mammals, intrinsic and extrinsic inhibitions of neuronal regeneration obstruct neural repair after spinal cord injury. Although astrocytes have...
2.
Saraswathy V, Zhou L, Mokalled M
Nat Commun . 2024 Aug; 15(1):6808. PMID: 39147780
Adult zebrafish have an innate ability to recover from severe spinal cord injury. Here, we report a comprehensive single nuclear RNA sequencing atlas that spans 6 weeks of regeneration. We...
3.
Shaw D, Saraswathy V, McAdow A, Zhou L, Park D, Mote R, et al.
bioRxiv . 2024 Jun; PMID: 38915507
Immune cells elicit a continuum of transcriptional and functional states after spinal cord injury (SCI). In mammals, inefficient debris clearance and chronic inflammation impede recovery and overshadow pro-regenerative immune functions....
4.
Burris B, Mokalled M
Methods Mol Biol . 2023 Sep; 2707:215-222. PMID: 37668915
Due to their renowned regenerative capacity, adult zebrafish are a premier vertebrate model to interrogate mechanisms of innate spinal cord regeneration. Following complete transection to their spinal cord, zebrafish extend...
5.
Jensen N, Burris B, Zhou L, Yamada H, Reyes C, Pincus Z, et al.
Front Mol Neurosci . 2023 Jul; 16:1155754. PMID: 37492522
Adult zebrafish are capable of anatomical and functional recovery following severe spinal cord injury. Axon growth, glial bridging and adult neurogenesis are hallmarks of cellular regeneration during spinal cord repair....
6.
Saraswathy V, Zhou L, Mokalled M
bioRxiv . 2023 Jun; PMID: 37292638
Adult zebrafish have an innate ability to recover from severe spinal cord injury. Here, we report a comprehensive single nuclear RNA sequencing atlas that spans 6 weeks of regeneration. We...
7.
Zhou L, McAdow A, Yamada H, Burris B, Shaw D, Oonk K, et al.
Development . 2023 May; 150(10). PMID: 37213080
Unlike mammals, adult zebrafish undergo spontaneous recovery after major spinal cord injury. Whereas reactive gliosis presents a roadblock for mammalian spinal cord repair, glial cells in zebrafish elicit pro-regenerative bridging...
8.
Jensen N, Burris B, Zhou L, Yamada H, Reyes C, Mokalled M
bioRxiv . 2023 Feb; PMID: 36778427
Adult zebrafish are capable of anatomical and functional recovery following severe spinal cord injury. Axon growth, glial bridging and adult neurogenesis are hallmarks of cellular regeneration during spinal cord repair....
9.
Feng R, Saraswathy V, Mokalled M, Cavalli V
Proc Natl Acad Sci U S A . 2023 Feb; 120(7):e2215906120. PMID: 36763532
Sensory neurons located in dorsal root ganglia (DRG) convey sensory information from peripheral tissue to the brain. After peripheral nerve injury, sensory neurons switch to a regenerative state to enable...
10.
Saraswathy V, Zhou L, McAdow A, Burris B, Dogra D, Reischauer S, et al.
Cell Rep . 2022 Nov; 41(8):111705. PMID: 36417881
Intrinsic and extrinsic inhibition of neuronal regeneration obstruct spinal cord (SC) repair in mammals. In contrast, adult zebrafish achieve functional recovery after complete SC transection. While studies of innate SC...