Maya Fedeli
Overview
Explore the profile of Maya Fedeli including associated specialties, affiliations and a list of published articles.
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Articles
17
Citations
290
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0
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Recent Articles
1.
Delfanti G, Cortesi F, Perini A, Antonini G, Azzimonti L, De Lalla C, et al.
Sci Immunol
. 2022 Aug;
7(74):eabn6563.
PMID: 35984893
Adoptive immunotherapy with T cells engineered with tumor-specific T cell receptors (TCRs) holds promise for cancer treatment. However, suppressive cues generated in the tumor microenvironment (TME) can hinder the efficacy...
2.
Faccani C, Rotta G, Clemente F, Fedeli M, Abbati D, Manfredi F, et al.
Life Sci Alliance
. 2022 Jun;
5(10).
PMID: 35724271
We describe a multi-step high-dimensional (HD) flow cytometry workflow for the deep phenotypic characterization of T cells infiltrating metastatic tumor lesions in the liver, particularly derived from colorectal cancer (CRC-LM)....
3.
Delfanti G, Dellabona P, Casorati G, Fedeli M
Front Med (Lausanne)
. 2022 May;
9:897750.
PMID: 35615083
Invariant Natural Killer T (iNKT) cells are T lymphocytes expressing a conserved semi-invariant TCR specific for lipid antigens (Ags) restricted for the monomorphic MHC class I-related molecule CD1d. iNKT cells...
4.
Fedeli M, Kuka M, Finardi A, Albano F, Vigano V, Iannacone M, et al.
Clin Transl Immunology
. 2021 Sep;
10(9):e1321.
PMID: 34584693
Objective: miR-21 is highly expressed in iNKT and activated T cells, but its T-cell autonomous functions are poorly defined. We sought to investigate the role of miR-21 in the development...
5.
Delfanti G, Perini A, Zappa E, Fedeli M
J Vis Exp
. 2021 Mar;
(168).
PMID: 33645564
Invariant Natural Killer T (iNKT) cells are innate-like T Lymphocytes expressing a conserved semi-invariant T cell receptor (TCR) specific for self or microbial lipid antigens presented by the non-polymorphic MHC...
6.
Finardi A, Diceglie M, Carbone L, Arno C, Mandelli A, De Santis G, et al.
Front Neurol
. 2020 Sep;
11:912.
PMID: 32973667
MicroRNAs (miRNAs) are single-stranded RNA that have key roles in the development of the immune system and are involved in the pathogenesis of various autoimmune diseases. We previously demonstrated that...
7.
Manfrini N, Ricciardi S, Miluzio A, Fedeli M, Scagliola A, Gallo S, et al.
Data Brief
. 2017 Sep;
14:653-658.
PMID: 28924581
The data described in this article are related to "High levels of eukaryotic Initiation Factor 6 (eIF6) are required for immune system homeostasis and for steering the glycolytic flux of...
8.
Manfrini N, Ricciardi S, Miluzio A, Fedeli M, Scagliola A, Gallo S, et al.
Dev Comp Immunol
. 2017 Jul;
77:69-76.
PMID: 28743432
Eukaryotic Initiation Factor 6 (eIF6) is required for 60S ribosomal subunit biogenesis and efficient initiation of translation. Intriguingly, in both mice and humans, endogenous levels of eIF6 are detrimental as...
9.
Fedeli M, Riba M, Manteiga J, Tian L, Vigano V, Rossetti G, et al.
Proc Natl Acad Sci U S A
. 2016 Dec;
113(51):E8286-E8295.
PMID: 27930306
Invariant natural killer T cells (iNKT) cells are T lymphocytes displaying innate effector functions, acquired through a distinct thymic developmental program regulated by microRNAs (miRNAs). Deleting miRNAs by Dicer ablation...
10.
Di Pietro C, De Giorgi L, Cosorich I, Sorini C, Fedeli M, Falcone M
J Immunol
. 2016 Sep;
197(8):3271-3280.
PMID: 27605013
NKT17 cells represent a functional subset of Vα14 invariant NKT (iNKT) cells with important effector functions in infections and autoimmune diseases. The mechanisms that drive NKT17 cell differentiation in the...