Massimiliano Pagani
Overview
Explore the profile of Massimiliano Pagani including associated specialties, affiliations and a list of published articles.
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Articles
74
Citations
3338
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0
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Recent Articles
1.
Ligorio F, Vingiani A, Torelli T, Sposetti C, Drufuca L, Iannelli F, et al.
Cell Metab
. 2024 Dec;
37(2):330-344.e7.
PMID: 39694040
In preclinical experiments, cyclic fasting-mimicking diets (FMDs) showed broad anticancer effects in combination with chemotherapy. Among different tumor types, triple-negative breast cancer (TNBC) is exquisitely sensitive to FMD. However, the...
2.
Pham V, Rodel C, Valentino M, Malinverno M, Paolini A, Munch J, et al.
EMBO Mol Med
. 2024 Oct;
16(11):2827-2855.
PMID: 39402138
Cerebral cavernous malformations (CCMs) are anomalies of the cerebral vasculature. Loss of the CCM proteins CCM1/KRIT1, CCM2, or CCM3/PDCD10 trigger a MAPK-Krüppel-like factor 2 (KLF2) signaling cascade, which induces a...
3.
Valentino M, Malinverno M, Maderna C, Pham V, Rodel C, Zanardi F, et al.
Circulation
. 2024 Aug;
150(9):738-741.
PMID: 39186529
No abstract available.
4.
Bastianello G, Kidiyoor G, Lowndes C, Li Q, Bonnal R, Godwin J, et al.
Proc Natl Acad Sci U S A
. 2024 Jul;
121(29):e2404551121.
PMID: 38990945
Confined cell migration hampers genome integrity and activates the ATR and ATM mechano-transduction pathways. We investigated whether the mechanical stress generated by metastatic interstitial migration contributes to the enhanced chromosomal...
5.
Oguchi A, Suzuki A, Komatsu S, Yoshitomi H, Bhagat S, Son R, et al.
Science
. 2024 Jul;
385(6704):eadd8394.
PMID: 38963856
Transcribed enhancer maps can reveal nuclear interactions underpinning each cell type and connect specific cell types to diseases. Using a 5' single-cell RNA sequencing approach, we defined transcription start sites...
6.
Schott M, Leon-Perinan D, Splendiani E, Strenger L, Licha J, Pentimalli T, et al.
Cell
. 2024 Jun;
187(15):3953-3972.e26.
PMID: 38917789
Spatial transcriptomics (ST) methods unlock molecular mechanisms underlying tissue development, homeostasis, or disease. However, there is a need for easy-to-use, high-resolution, cost-efficient, and 3D-scalable methods. Here, we report Open-ST, a...
7.
Toninelli M, Rossetti G, Pagani M
Trends Cancer
. 2023 Sep;
9(12):1085-1096.
PMID: 37673713
In recent years technologies that can achieve readouts at cellular resolution such as single-cell RNA sequencing (scRNA-seq) have provided a comprehensive characterization of the cellular proportions and phenotypes that populate...
8.
Paroni M, Leccese G, Ranzani V, Moschetti G, Chiara M, Perillo F, et al.
J Crohns Colitis
. 2023 Jul;
17(12):1988-2001.
PMID: 37462681
IFNγ-producing ex-Th17 cells ['Th1/17'] were shown to play a key pathogenic role in experimental colitis and are abundant in the intestine. Here, we identified and characterised a novel, potentially colitogenic...
9.
Della Chiara G, Pagani M
Methods Mol Biol
. 2023 May;
2655:231-244.
PMID: 37213001
In the recent years, the establishment of self-organizing 3D cultures (organoids) generated from human primary tissues added a novel and physiological viewpoint to interrogate basic and pathological matters. Indeed, these...
10.
Raccosta L, Marinozzi M, Costantini S, Maggioni D, Ferreira L, Corna G, et al.
Cell Death Dis
. 2023 Feb;
14(2):129.
PMID: 36792589
Lipid and cholesterol metabolism play a crucial role in tumor cell behavior and in shaping the tumor microenvironment. In particular, enzymatic and non-enzymatic cholesterol metabolism, and derived metabolites control dendritic...