Maximilien Grandclaudon
Overview
Explore the profile of Maximilien Grandclaudon including associated specialties, affiliations and a list of published articles.
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Articles
14
Citations
342
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0
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Recent Articles
1.
Sirven P, Faucheux L, Grandclaudon M, Michea P, Vincent-Salomon A, Mechta-Grigoriou F, et al.
Breast Cancer Res
. 2022 Dec;
24(1):94.
PMID: 36539890
Background: During cancer development, the normal tissue microenvironment is shaped by tumorigenic events. Inflammatory mediators and immune cells play a key role during this process. However, which molecular features most...
2.
Fang L, Ford-Roshon D, Russo M, OBrien C, Xiong X, Gurjao C, et al.
Nat Commun
. 2022 Jun;
13(1):3181.
PMID: 35676246
The RNF43_p.G659fs mutation occurs frequently in colorectal cancer, but its function remains poorly understood and there are no specific therapies directed against this alteration. In this study, we find that...
3.
Hoffmann C, Noel F, Grandclaudon M, Massenet-Regad L, Michea P, Sirven P, et al.
Nat Commun
. 2022 Apr;
13(1):1983.
PMID: 35418195
Dendritic cells (DC) are traditionally classified according to their ontogeny and their ability to induce T cell response to antigens, however, the phenotypic and functional state of these cells in...
4.
Peper-Gabriel J, Pavlidou M, Pattarini L, Morales-Kastresana A, Jaquin T, Gallou C, et al.
Clin Cancer Res
. 2022 Feb;
28(15):3387-3399.
PMID: 35121624
Purpose: While patients responding to checkpoint blockade often achieve remarkable clinical responses, there is still significant unmet need due to resistant or refractory tumors. A combination of checkpoint blockade with...
5.
Corral-Jara K, Chauvin C, Abou-Jaoude W, Grandclaudon M, Naldi A, Soumelis V, et al.
Mol Biomed
. 2022 Jan;
2(1):9.
PMID: 35006414
Interleukins (IL)-17A and F are critical cytokines in anti-microbial immunity but also contribute to auto-immune pathologies. Recent evidence suggests that they may be differentially produced by T-helper (Th) cells, but...
6.
Kim M, Ly S, Xie Y, Duronio G, Ford-Roshon D, Hwang J, et al.
Dev Cell
. 2022 Jan;
57(2):212-227.e8.
PMID: 34990589
The transcriptional co-activator YAP1 oncogene is the downstream effector of the Hippo pathway, which regulates tissue homeostasis, organ size, regeneration, and tumorigenesis. Multiple cancers are dependent on sustained expression of...
7.
Karpf L, Trichot C, Faucheux L, Legbre I, Grandclaudon M, Lahoute C, et al.
Cell Discov
. 2022 Jan;
8(1):1.
PMID: 34983927
Cells receive, and adjust to, various stimuli, which function as part of complex microenvironments forming their "context". The possibility that a given context impacts the response to a given stimulus...
8.
Noel F, Massenet-Regad L, Carmi-Levy I, Cappuccio A, Grandclaudon M, Trichot C, et al.
Nat Commun
. 2021 Feb;
12(1):1089.
PMID: 33597528
Cell-to-cell communication can be inferred from ligand-receptor expression in cell transcriptomic datasets. However, important challenges remain: global integration of cell-to-cell communication; biological interpretation; and application to individual cell population transcriptomic...
9.
Trichot C, Faucheux L, Karpf L, Grandclaudon M, Pattarini L, Bagot M, et al.
J Allergy Clin Immunol
. 2020 Jun;
147(2):756-759.
PMID: 32526313
No abstract available.
10.
Grandclaudon M, Perrot-Dockes M, Trichot C, Karpf L, Abouzid O, Chauvin C, et al.
Cell
. 2019 Oct;
179(2):432-447.e21.
PMID: 31585082
Cell-cell communication involves a large number of molecular signals that function as words of a complex language whose grammar remains mostly unknown. Here, we describe an integrative approach involving (1)...