Maximilian Lennartz
Overview
Explore the profile of Maximilian Lennartz including associated specialties, affiliations and a list of published articles.
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87
Citations
552
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Recent Articles
11.
Scherzai S, Lennartz M, Jacobsen F, Viehweger F, Dum D, Menz A, et al.
Pathol Res Pract
. 2024 Nov;
264:155676.
PMID: 39520970
The protein gene product 9.5 (PGP9.5), also termed ubiquitin C-terminal hydrolase L1 (UCH-L1) is an important component of the ubiquitination/deubiquitination system and plays a role in axonal transport. To comprehensively...
12.
Lutz F, Han S, Buyucek S, Moller K, Viehweger F, Schlichter R, et al.
Diagnostics (Basel)
. 2024 Oct;
14(19).
PMID: 39410561
Trefoil factor 1 (TFF1) plays a role in the mucus barrier. To evaluate the prevalence of TFF1 expression in cancer, a tissue microarray containing 18,878 samples from 149 tumor types...
13.
Moller K, Gulzar T, Lennartz M, Viehweger F, Kluth M, Hube-Magg C, et al.
Virchows Arch
. 2024 Oct;
485(5):815-828.
PMID: 39377914
Thyroid transcription factor 1 (TTF-1) immunohistochemistry (IHC) is routinely used for the distinction of primary pulmonary adenocarcinomas. However, TTF-1 can also occur in other malignancies. A tissue microarray containing 17,772...
14.
Kluth M, Hitzschke M, Furlano K, Plage H, Hofbauer S, Weinberger S, et al.
Genes Chromosomes Cancer
. 2024 Sep;
63(9):e23271.
PMID: 39324446
17p13 deletions including TP53 and other genes represent a common cause for reduced/lost p53 function in tumor cells. In this study, we analyzed the impact of 17p13 (TP53) deletions and...
15.
Gorbokon N, Wossner N, Lennartz M, Rico S, Kind S, Reiswich V, et al.
Am J Surg Pathol
. 2024 Aug;
48(10):1245-1258.
PMID: 39132873
Loss of S-methyl-5'-thioadenosine phosphorylase (MTAP) expression is a common event in cancer leading to a critical vulnerability of cancer cells towards anti-cancer drugs. Homozygous MTAP deletions result in a complete...
16.
Gorbokon N, Baltruschat S, Lennartz M, Luebke A, Hoflmayer D, Kluth M, et al.
Virchows Arch
. 2024 Aug;
485(3):491-507.
PMID: 39105782
PAX8 plays a role in development of the thyroid, kidney, and the Wolffian and Mullerian tract. In surgical pathology, PAX8 immunohistochemistry is used to determine tumors of renal and ovarian...
17.
Westhaeusser F, Fuhlert P, Dietrich E, Lennartz M, Khatri R, Kaiser N, et al.
medRxiv
. 2024 Jul;
PMID: 39040171
Background: Prostate cancer (PCa) is among the most common cancers in men and its diagnosis requires the histopathological evaluation of biopsies by human experts. While several recent artificial intelligence-based (AI)...
18.
Menz A, Zerneke J, Viehweger F, Buyucek S, Dum D, Schlichter R, et al.
Cancers (Basel)
. 2024 Jul;
16(13).
PMID: 39001487
Stimulator of interferon genes protein (STING) activates the immune response in inflammatory cells. STING expression in cancer cells is less well characterized, but STING agonists are currently being evaluated as...
19.
Kind S, Castillo C, Schlichter R, Gorbokon N, Lennartz M, Hornsteiner L, et al.
BMC Cancer
. 2024 Jul;
24(1):794.
PMID: 38961454
Background: Kallikrein-related peptidase 7 (KLK7) is a chymotrypsin-like serine protease which is essential for the desquamation of corneocytes and thus plays a pivotal role in maintaining skin homeostasis. In cancer,...
20.
Plage H, Furlano K, Neymeyer J, Weinberger S, Gerdes B, Hubatsch M, et al.
BJUI Compass
. 2024 Jun;
5(6):585-592.
PMID: 38873357
Objectives: Carcinoembryonic antigen (CEA) is a cell surface glycoprotein that represents a promising therapeutic target. Serum measurement of shedded CEA can be utilized for monitoring of cancer patients. Material And...