Maxim V C Greenberg
Overview
Explore the profile of Maxim V C Greenberg including associated specialties, affiliations and a list of published articles.
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Articles
24
Citations
1747
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0
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Recent Articles
1.
Richard Albert J, Urli T, Monteagudo-Sanchez A, Le Breton A, Sultanova A, David A, et al.
Nat Struct Mol Biol
. 2024 Oct;
32(2):346-357.
PMID: 39448850
In mammals, 5-methylcytosine (5mC) and Polycomb repressive complex 2 (PRC2)-deposited histone 3 lysine 27 trimethylation (H3K27me3) are generally mutually exclusive at CpG-rich regions. As mouse embryonic stem cells exit the...
2.
Monteagudo-Sanchez A, Richard Albert J, Scarpa M, Noordermeer D, Greenberg M
Nucleic Acids Res
. 2024 Aug;
52(18):10934-10950.
PMID: 39180406
During mammalian embryogenesis, both the 5-cytosine DNA methylation (5meC) landscape and three dimensional (3D) chromatin architecture are profoundly remodeled during a process known as 'epigenetic reprogramming.' An understudied aspect of...
3.
Monteagudo-Sanchez A, Noordermeer D, Greenberg M
Nat Struct Mol Biol
. 2024 Mar;
31(3):404-412.
PMID: 38499830
Cytosine DNA methylation is a highly conserved epigenetic mark in eukaryotes. Although the role of DNA methylation at gene promoters and repetitive elements has been extensively studied, the function of...
4.
Schulz M, Teissandier A, De La Mata Santaella E, Armand M, Iranzo J, El Marjou F, et al.
Nat Struct Mol Biol
. 2024 Jan;
31(1):102-114.
PMID: 38177678
As embryonic stem cells (ESCs) transition from naive to primed pluripotency during early mammalian development, they acquire high DNA methylation levels. During this transition, the germline is specified and undergoes...
5.
Canat A, Veillet A, Batrin R, Dubourg C, Lhoumaud P, Arnau-Romero P, et al.
J Cell Sci
. 2023 Sep;
136(19).
PMID: 37655670
Genomes comprise a large fraction of repetitive sequences folded into constitutive heterochromatin, which protect genome integrity and cell identity. De novo formation of heterochromatin during preimplantation development is an essential...
6.
Yakhou L, Azogui A, Gupta N, Richard Albert J, Miura F, Ferry L, et al.
Nucleic Acids Res
. 2023 Aug;
51(19):10292-10308.
PMID: 37650637
Epigenetic mechanisms are essential to establish and safeguard cellular identities in mammals. They dynamically regulate the expression of genes, transposable elements and higher-order chromatin structures. Consequently, these chromatin marks are...
7.
Gupta N, Yakhou L, Richard Albert J, Azogui A, Ferry L, Kirsh O, et al.
Nat Struct Mol Biol
. 2023 Jul;
30(8):1105-1118.
PMID: 37488355
In mammals, only the zygote and blastomeres of the early embryo are totipotent. This totipotency is mirrored in vitro by mouse '2-cell-like cells' (2CLCs), which appear at low frequency in...
8.
Richard Albert J, Greenberg M
Development
. 2023 Jun;
150(12).
PMID: 37309910
Classical genomic imprints are regulated by parent-specific DNA methylation levels inherited from the gametes in mammals. Imprints control gene expression in a parent-of-origin manner and are essential for development. A...
9.
Richard Albert J, Kobayashi T, Inoue A, Monteagudo-Sanchez A, Kumamoto S, Takashima T, et al.
Genome Biol
. 2023 Mar;
24(1):48.
PMID: 36918927
Background: Genomic imprinting affects gene expression in a parent-of-origin manner and has a profound impact on complex traits including growth and behavior. While the rat is widely used to model...
10.
Dubois A, Vincenti L, Chervova A, Greenberg M, Vandormael-Pournin S, Bourchis D, et al.
Development
. 2022 Aug;
149(17).
PMID: 35976266
Mouse embryonic stem cells have an inherent propensity to explore gene regulatory states associated with either self-renewal or differentiation. This property depends on ERK, which downregulates pluripotency genes such as...