Maxim Imakaev
Overview
Explore the profile of Maxim Imakaev including associated specialties, affiliations and a list of published articles.
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37
Citations
9376
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Recent Articles
1.
Abdennur N, Fudenberg G, Flyamer I, Galitsyna A, Goloborodko A, Imakaev M, et al.
PLoS Comput Biol
. 2024 May;
20(5):e1012164.
PMID: 38809952
The field of 3D genome organization produces large amounts of sequencing data from Hi-C and a rapidly-expanding set of other chromosome conformation protocols (3C+). Massive and heterogeneous 3C+ data require...
2.
Polovnikov K, Slavov B, Belan S, Imakaev M, Brandao H, Mirny L
Phys Rev X
. 2024 May;
13(4).
PMID: 38774252
Chromosomes are exceedingly long topologically-constrained polymers compacted in a cell nucleus. We recently suggested that chromosomes are organized into loops by an active process of loop extrusion. Yet loops remain...
3.
Abdennur N, Abraham S, Fudenberg G, Flyamer I, Galitsyna A, Goloborodko A, et al.
PLoS Comput Biol
. 2024 May;
20(5):e1012067.
PMID: 38709825
Chromosome conformation capture (3C) technologies reveal the incredible complexity of genome organization. Maps of increasing size, depth, and resolution are now used to probe genome architecture across cell states, types,...
4.
Abdennur N, Fudenberg G, Flyamer I, Galitsyna A, Goloborodko A, Imakaev M, et al.
Bioinformatics
. 2024 Feb;
40(2).
PMID: 38402507
Motivation: Genomic intervals are one of the most prevalent data structures in computational genome biology, and used to represent features ranging from genes, to DNA binding sites, to disease variants....
5.
Abdennur N, Fudenberg G, Flyamer I, Galitsyna A, Goloborodko A, Imakaev M, et al.
bioRxiv
. 2023 Feb;
PMID: 36824968
The field of 3D genome organization produces large amounts of sequencing data from Hi-C and a rapidly-expanding set of other chromosome conformation protocols (3C+). Massive and heterogeneous 3C+ data require...
6.
Spracklin G, Abdennur N, Imakaev M, Chowdhury N, Pradhan S, Mirny L, et al.
Nat Struct Mol Biol
. 2022 Dec;
30(1):38-51.
PMID: 36550219
The relationships between chromosomal compartmentalization, chromatin state and function are poorly understood. Here by profiling long-range contact frequencies in HCT116 colon cancer cells, we distinguish three silent chromatin states, comprising...
7.
Duvallet C, Wu F, McElroy K, Imakaev M, Endo N, Xiao A, et al.
ACS ES T Water
. 2022 Nov;
2(11):1899-1909.
PMID: 36380771
Wastewater-based epidemiology has emerged as a promising technology for population-level surveillance of COVID-19. In this study, we present results of a large nationwide SARS-CoV-2 wastewater monitoring system in the United...
8.
Baaijens J, Zulli A, Ott I, Nika I, van der Lugt M, Petrone M, et al.
Genome Biol
. 2022 Nov;
23(1):236.
PMID: 36348471
Effectively monitoring the spread of SARS-CoV-2 mutants is essential to efforts to counter the ongoing pandemic. Predicting lineage abundance from wastewater, however, is technically challenging. We show that by sequencing...
9.
Reiff S, Schroeder A, Kirli K, Cosolo A, Bakker C, Mercado L, et al.
Nat Commun
. 2022 Nov;
13(1):6561.
PMID: 36323678
No abstract available.
10.
Reiff S, Schroeder A, Kirli K, Cosolo A, Bakker C, Mercado L, et al.
Nat Commun
. 2022 May;
13(1):2365.
PMID: 35501320
The 4D Nucleome (4DN) Network aims to elucidate the complex structure and organization of chromosomes in the nucleus and the impact of their disruption in disease biology. We present the...