Max Hallin
Overview
Explore the profile of Max Hallin including associated specialties, affiliations and a list of published articles.
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Articles
4
Citations
101
Followers
0
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Recent Articles
1.
Msaouel P, Yu K, Yuan Y, Chen J, Yan X, Karki M, et al.
Nat Commun
. 2025 Jan;
16(1):578.
PMID: 39794332
We conducted a phase I trial to determine the optimal dose of triplet therapy with the tyrosine kinase inhibitor sitravatinib plus nivolumab plus ipilimumab in 22 previously untreated patients with...
2.
Karam J, Msaouel P, Haymaker C, Matin S, Campbell M, Zurita A, et al.
Nat Commun
. 2023 May;
14(1):2684.
PMID: 37164948
Sitravatinib is an immunomodulatory tyrosine kinase inhibitor that can augment responses when combined with programmed death-1 inhibitors such as nivolumab. We report a single-arm, interventional, phase 2 study of neoadjuvant...
3.
Liu S, Gu Y, Pascual B, Yan Z, Hallin M, Zhang C, et al.
Blood Adv
. 2018 Jan;
1(15):1088-1100.
PMID: 29296751
The chemokine receptor CXCR4 is highly expressed and associated with poor prognosis in multiple malignancies. Upon engagement by its ligand, CXCL12, CXCR4 triggers intracellular signaling pathways that control trafficking of...
4.
Kashyap M, Amaya-Chanaga C, Kumar D, Simmons B, Huser N, Gu Y, et al.
J Hematol Oncol
. 2017 May;
10(1):112.
PMID: 28526063
Background: The CXCR4-CXCL12 axis plays an important role in the chronic lymphocytic leukemia (CLL)-microenvironment interaction. Overexpression of CXCR4 has been reported in different hematological malignancies including CLL. Binding of the...
5.
Zhang C, Yan Z, Painter C, Zhang Q, Chen E, Arango M, et al.
Clin Cancer Res
. 2009 Jul;
15(14):4630-40.
PMID: 19584159
Purpose: Checkpoint kinase 1 (Chk1) plays a critical role in the activation of mitotic spindle checkpoint and DNA damage checkpoint. We examined the preclinical use of the Chk1 inhibitor PF-00477736...