Max Flottmann
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Explore the profile of Max Flottmann including associated specialties, affiliations and a list of published articles.
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11
Citations
153
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Recent Articles
1.
Seeger M, Flottmann M, Klipp E
Heliyon
. 2023 Feb;
9(2):e13101.
PMID: 36793957
Translation is a central step in gene expression, however its quantitative and time-resolved regulation is poorly understood. We developed a discrete, stochastic model for protein translation in in a whole-transcriptome,...
2.
Teufel L, Tummler K, Flottmann M, Herrmann A, Barkai N, Klipp E
Sci Rep
. 2019 Mar;
9(1):3343.
PMID: 30833602
Oscillating gene expression is crucial for correct timing and progression through cell cycle. In Saccharomyces cerevisiae, G1 cyclins Cln1-3 are essential drivers of the cell cycle and have an important...
3.
Schelker M, Mair C, Jolmes F, Welke R, Klipp E, Herrmann A, et al.
PLoS Comput Biol
. 2016 Oct;
12(10):e1005075.
PMID: 27780209
After endocytic uptake, influenza viruses transit early endosomal compartments and eventually reach late endosomes. There, the viral glycoprotein hemagglutinin (HA) triggers fusion between endosomal and viral membrane, a critical step...
4.
Mori T, Flottmann M, Krantz M, Akutsu T, Klipp E
BMC Syst Biol
. 2015 Aug;
9:45.
PMID: 26259567
Background: Cellular decision-making is governed by molecular networks that are highly complex. An integrative understanding of these networks on a genome wide level is essential to understand cellular health and...
5.
Kummer S, Flottmann M, Schwanhausser B, Sieben C, Veit M, Selbach M, et al.
PLoS One
. 2014 Apr;
9(4):e94257.
PMID: 24718678
We studied the dynamics of the proteome of influenza virus A/PR/8/34 (H1N1) infected Madin-Darby canine kidney cells up to 12 hours post infection by mass spectrometry based quantitative proteomics using...
6.
Flottmann M, Krause F, Klipp E, Krantz M
BMC Syst Biol
. 2013 Jul;
7:58.
PMID: 23835289
Background: Intracellular signalling systems are highly complex, rendering mathematical modelling of large signalling networks infeasible or impractical. Boolean modelling provides one feasible approach to whole-network modelling, but at the cost...
7.
Krause F, Schulz M, Ripkens B, Flottmann M, Krantz M, Klipp E, et al.
Bioinformatics
. 2013 Apr;
29(11):1467-8.
PMID: 23574737
Motivation: The rapid accumulation of knowledge in the field of Systems Biology during the past years requires advanced, but simple-to-use, methods for the visualization of information in a structured and...
8.
Flottmann M, Scharp T, Klipp E
Front Physiol
. 2012 Jul;
3:216.
PMID: 22754535
Somatic cell reprogramming has dramatically changed stem cell research in recent years. The high pace of new findings in the field and an ever increasing amount of data from new...
9.
Molecular insights into reprogramming-initiation events mediated by the OSKM gene regulatory network
Mah N, Wang Y, Liao M, Prigione A, Jozefczuk J, Lichtner B, et al.
PLoS One
. 2011 Sep;
6(8):e24351.
PMID: 21909390
Somatic cells can be reprogrammed to induced pluripotent stem cells by over-expression of OCT4, SOX2, KLF4 and c-MYC (OSKM). With the aim of unveiling the early mechanisms underlying the induction...
10.
Schaber J, Flottmann M, Li J, Tiger C, Hohmann S, Klipp E
PLoS One
. 2011 Apr;
6(3):e14791.
PMID: 21483474
In systems biology uncertainty about biological processes translates into alternative mathematical model candidates. Here, the goal is to generate, fit and discriminate several candidate models that represent different hypotheses for...