Mauro Torres
Overview
Explore the profile of Mauro Torres including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
13
Citations
83
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Torres M, Hawke E, Hoare R, Scholey R, Pybus L, Young A, et al.
Metab Eng
. 2024 Dec;
88:25-39.
PMID: 39643154
Lactate metabolism plays a critical role in mammalian cell bioprocessing, influencing cellular performance and productivity. The transition from lactate production to consumption, known as lactate metabolic shift, is highly beneficial...
2.
Torres M, Mcconnaughie D, Akhtar S, Gaffney C, Fievet B, Ingham C, et al.
Metab Eng
. 2024 Feb;
82:89-99.
PMID: 38325641
Precise control over mammalian cell growth dynamics poses a major challenge in biopharmaceutical manufacturing. Here, we present a multi-level cell engineering strategy for the tunable regulation of growth phases in...
3.
Torres M, Betts Z, Scholey R, Elvin M, Place S, Hayes A, et al.
Biotechnol Bioeng
. 2023 Apr;
120(9):2389-2402.
PMID: 37060548
Phenotypic stability of Chinese hamster ovary (CHO) cells over long term culture (LTC) presents one of the most pressing challenges in the development of therapeutic protein manufacturing processess. However, our...
4.
Latorre Y, Torres M, Vergara M, Berrios J, Sampayo M, Godecke N, et al.
Sci Rep
. 2023 Jan;
13(1):1482.
PMID: 36707606
Improving the cellular capacity of Chinese hamster ovary (CHO) cells to produce large amounts of therapeutic proteins remains a major challenge for the biopharmaceutical industry. In previous studies, we observed...
5.
Avello V, Torres M, Vergara M, Berrios J, Valdez-Cruz N, Acevedo C, et al.
PLoS One
. 2022 Nov;
17(11):e0277620.
PMID: 36374852
Low temperature and sodium butyrate (NaBu) are two of the most used productivity-enhancing strategies in CHO cell cultures during biopharmaceutical manufacturing. While these two approaches alter the balance in the...
6.
Torres M, Hussain H, Dickson A
Crit Rev Biotechnol
. 2022 Apr;
43(4):628-645.
PMID: 35465810
Mammalian cell factories (in particular the CHO cell system) have been crucial in the rise of biopharmaceuticals. Mammalian cells have compartmentalized organelles where intricate networks of proteins manufacture highly sophisticated...
7.
Torres M, Dickson A
Metab Eng
. 2021 Dec;
69:249-261.
PMID: 34929420
The deficient secretory phenotype of Chinese hamster ovary (CHO) cells is a major limitation for high-level production of biopharmaceuticals, particularly for those with complex molecular architectures and post-translational modifications. To...
8.
Torres M, Dickson A
Biotechnol Bioeng
. 2021 Nov;
119(2):550-565.
PMID: 34821376
Environmental growth-inhibition conditions (GICs) have been used extensively for increasing cell-specific productivity (q ) of Chinese hamster ovary (CHO) cells, with the most common being temperature downshift and sodium butyrate...
9.
Torres M, Dickson A
Metab Eng
. 2021 Jul;
67:237-249.
PMID: 34265400
Chinese hamster ovary (CHO) cells present inherent limitations for processing and secretion of large amounts of recombinant proteins, especially for those requiring complex post-translational processing. To tackle these limitations, we...
10.
Torres M, Elvin M, Betts Z, Place S, Gaffney C, Dickson A
Biotechnol Prog
. 2020 Nov;
37(2):e3099.
PMID: 33169492
Culture systems based on spin tube reactors have been consolidated in the development of manufacturing processes based on Chinese hamster ovary (CHO) cells. Despite their widespread use, there is little...