Mauro Marigo
Overview
Explore the profile of Mauro Marigo including associated specialties, affiliations and a list of published articles.
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25
Citations
455
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Recent Articles
1.
Ascic E, Marigo M, David L, Frisch Herrik K, Grupe M, Hougaard C, et al.
J Med Chem
. 2024 Nov;
67(22):20135-20155.
PMID: 39560374
The discovery of d-cycloserine (), a partial agonist of the NMDA receptor that exhibits antidepressant effects without the psychotomimetic effects of ketamine, has fueled interest in new NMDA-targeting antidepressants. Our...
2.
Fjelbye K, Marigo M, Clausen R, Jorgensen E, Christoffersen C, Juhl K
Medchemcomm
. 2018 Aug;
9(5):893-896.
PMID: 30108979
P-Glycoprotein (Pgp)-mediated cellular efflux is recognized as a common challenge in CNS drug discovery. In this study, the influence of replacing a hydrogen atom with fluorine on the p and...
3.
Fjelbye K, Marigo M, Clausen R, Juhl K
Org Lett
. 2016 Feb;
18(5):1170-3.
PMID: 26902535
A practical diastereodivergent access to β-fluoropyrrolidines with two adjacent stereocenters has been demonstrated, by either enhancing or completely reversing the substrate control, in the diastereoselective fluorination of a series of...
4.
Melchiorre P, Marigo M, Carlone A, Bartoli G
Angew Chem Int Ed Engl
. 2008 Jul;
47(33):6138-71.
PMID: 18666089
Catalysis with chiral secondary amines (asymmetric aminocatalysis) has become a well-established and powerful synthetic tool for the chemo- and enantioselective functionalization of carbonyl compounds. In the last eight years alone,...
5.
Diner P, Nielsen M, Marigo M, Anker Jorgensen K
Angew Chem Int Ed Engl
. 2007 Feb;
46(12):1983-7.
PMID: 17286332
No abstract available.
6.
Carlone A, Cabrera S, Marigo M, Anker Jorgensen K
Angew Chem Int Ed Engl
. 2006 Dec;
46(7):1101-4.
PMID: 17195269
No abstract available.
7.
Carlone A, Marigo M, North C, Landa A, Anker Jorgensen K
Chem Commun (Camb)
. 2006 Dec;
(47):4928-30.
PMID: 17136250
Optically active 2,5-disubstituted-cyclohexen-2-one derivatives have been prepared in a one-pot process consisting of five reaction steps: an organocatalytic asymmetric conjugated addition of beta-ketoesters to alpha,beta-unsaturated aldehydes that proceeds in aqueous...
8.
Bertelsen S, Marigo M, Brandes S, Diner P, Anker Jorgensen K
J Am Chem Soc
. 2006 Sep;
128(39):12973-80.
PMID: 17002394
A new concept in organocatalysis is presented, the direct asymmetric gamma-functionalization of alpha,beta-unsaturated aldehydes. We disclose that secondary amines can invert the usual reactivity of alpha,beta-unsaturated aldehydes, enabling a direct...
9.
Marigo M, Anker Jorgensen K
Chem Commun (Camb)
. 2006 Jun;
(19):2001-11.
PMID: 16767258
The direct enantioselective introduction of a stereogenic carbon-heteroatom bond adjacent to a carbonyl functionality leads to optically active compounds of significant importance for e.g. the life-science industry. Organocatalytic enantioselective amination,...
10.
Brandau S, Landa A, Franzen J, Marigo M, Anker Jorgensen K
Angew Chem Int Ed Engl
. 2006 Apr;
45(26):4305-9.
PMID: 16646104
No abstract available.