Maurice van Eis
Overview
Explore the profile of Maurice van Eis including associated specialties, affiliations and a list of published articles.
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Articles
3
Citations
57
Followers
0
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Recent Articles
1.
Thoma G, Blanz J, Buhlmayer P, Druckes P, Kittelmann M, Smith A, et al.
Bioorg Med Chem Lett
. 2014 Apr;
24(10):2278-82.
PMID: 24726806
We describe two series of Syk inhibitors which potently abrogate Syk kinase function in enzymatic assays, cellular assays and in primary cells in the presence of blood. Introduction of a...
2.
Meredith E, Beattie K, Burgis R, Capparelli M, Chapo J, DiPietro L, et al.
J Med Chem
. 2010 Aug;
53(15):5422-38.
PMID: 20684592
The synthesis and biological evaluation of potent and selective PKD inhibitors are described herein. The compounds described in the present study selectively inhibit PKD among other putative HDAC kinases. The...
3.
Meredith E, Ardayfio O, Beattie K, Dobler M, Enyedy I, Gaul C, et al.
J Med Chem
. 2010 Aug;
53(15):5400-21.
PMID: 20684591
A novel 2,6-naphthyridine was identified by high throughput screen (HTS) as a dual protein kinase C/D (PKC/PKD) inhibitor. PKD inhibition in the heart was proposed as a potential antihypertrophic mechanism...