Mattia Forcato
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Explore the profile of Mattia Forcato including associated specialties, affiliations and a list of published articles.
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Recent Articles
11.
Grandi F, Caroli J, Romano O, Marchionni M, Forcato M, Bicciato S
J Mol Biol
. 2022 Jun;
434(11):167560.
PMID: 35662457
The advent of single-cell sequencing is providing unprecedented opportunities to disentangle tissue complexity and investigate cell identities and functions. However, the analysis of single cell data is a challenging, multi-step...
12.
Barravecchia I, De Cesari C, Forcato M, Scebba F, Pyankova O, Bridger J, et al.
Cell Mol Life Sci
. 2021 Dec;
79(1):28.
PMID: 34936031
Microgravity and space radiation (SR) are two highly influential factors affecting humans in space flight (SF). Many health problems reported by astronauts derive from endothelial dysfunction and impaired homeostasis. Here,...
13.
Sartori G, Napoli S, Cascione L, Chung E, Priebe V, Arribas A, et al.
J Exp Clin Cancer Res
. 2021 Nov;
40(1):357.
PMID: 34763718
Background: Diffuse large B-cell lymphoma (DLBCL) comprises at least two main biologically distinct entities: germinal center B-cell (GCB) and activated B-cell (ABC) subtype. Albeit sharing common lesions, GCB and ABC...
14.
Dori M, Forcato M
Methods Mol Biol
. 2021 Aug;
2301:209-234.
PMID: 34415538
HiChIP is a novel method for the analysis of chromatin interactions based on in situ Hi-C that adds an immuno-precipitation (ChIP) step for the investigation of chromatin structures driven by...
15.
Pezze L, Meskyte E, Forcato M, Pontalti S, Badowska K, Rizzotto D, et al.
Cell Death Dis
. 2021 Jul;
12(8):742.
PMID: 34315857
Cancer stem cells (CSCs) represent a population of cells within the tumor able to drive tumorigenesis and known to be highly resistant to conventional chemotherapy and radiotherapy. In this work,...
16.
Shytaj I, Procopio F, Tarek M, Carlon-Andres I, Tang H, Goldman A, et al.
EMBO Mol Med
. 2021 Jul;
13(8):e13901.
PMID: 34289240
HIV-1 infects lymphoid and myeloid cells, which can harbor a latent proviral reservoir responsible for maintaining lifelong infection. Glycolytic metabolism has been identified as a determinant of susceptibility to HIV-1...
17.
Napoli S, Cascione L, Rinaldi A, Spriano F, Guidetti F, Zhang F, et al.
Haematologica
. 2021 Jun;
107(5):1131-1143.
PMID: 34162177
Enhancers are regulatory regions of DNA, which play a key role in cell-type specific differentiation and development. Most active enhancers are transcribed into enhancer RNA (eRNA) that can regulate transcription...
18.
Enzo E, Secone Seconetti A, Forcato M, Tenedini E, Polito M, Sala I, et al.
Nat Commun
. 2021 May;
12(1):2505.
PMID: 33947848
Autologous epidermal cultures restore a functional epidermis on burned patients. Transgenic epidermal grafts do so also in genetic skin diseases such as Junctional Epidermolysis Bullosa. Clinical success strictly requires an...
19.
Lo Tartaro D, De Biasi S, Forcato M, Gibellini L, Cossarizza A
Methods Mol Biol
. 2021 Apr;
2285:277-296.
PMID: 33928560
During the last decade, the rapid progress in the development of next-generation sequencing (NGS) technologies has provided relevant insights into complex biological systems, ranging from cancer genomics to microbiology. Among...
20.
Della Chiara G, Gervasoni F, Fakiola M, Godano C, DOria C, Azzolin L, et al.
Nat Commun
. 2021 Apr;
12(1):2340.
PMID: 33879786
Cancer is characterized by pervasive epigenetic alterations with enhancer dysfunction orchestrating the aberrant cancer transcriptional programs and transcriptional dependencies. Here, we epigenetically characterize human colorectal cancer (CRC) using de novo...