Mattia Capulli
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Explore the profile of Mattia Capulli including associated specialties, affiliations and a list of published articles.
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34
Citations
779
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Recent Articles
1.
Latini A, Borgiani P, De Benedittis G, Ciccacci C, Novelli L, Pepe G, et al.
Gene
. 2024 Feb;
907:148279.
PMID: 38360126
The identification of rare genetic variants associated to Systemic Lupus Erythematosus (SLE) could also help to understand the pathogenic mechanisms at the basis of the disease. In this study we...
2.
Volpe E, Corda L, Tommaso E, Pelliccia F, Ottalevi R, Licastro D, et al.
bioRxiv
. 2024 Jan;
PMID: 38168337
Comparative analysis of recent human genome assemblies highlights profound sequence divergence that peaks within polymorphic loci such as centromeres. This raises the question about the adequacy of relying on human...
3.
Luo N, Mosialou I, Capulli M, Bisikirska B, Lin C, Huang Y, et al.
J Clin Invest
. 2022 Oct;
132(23).
PMID: 36194488
The various functions of the skeleton are influenced by extracellular cues, hormones, and neurotransmitters. One type of neuronal regulation favors bone mass accrual by inhibiting sympathetic nervous system (SNS) activity....
4.
Ventura L, Arrizza L, Quaresima R, Capulli M
Pathologica
. 2022 Sep;
114(4):339-341.
PMID: 36136903
The renal stone found in the natural mummy of an anonymous nobleman dating to 19 century was investigated using advanced imaging modalities and analytic investigations. By this multidisciplinary approach we...
5.
Paganini C, Gramegna Tota C, Monti L, Monti I, Maurizi A, Capulli M, et al.
Biochem Pharmacol
. 2021 Feb;
185:114452.
PMID: 33545117
Diastrophic dysplasia (DTD) is a recessive chondrodysplasia caused by mutations in the SLC26A2 gene encoding for a sulfate/chloride transporter. When SLC26A2 is impaired intracellular level of sulfate is reduced leading...
6.
Bishop R, Marino S, Carrasco G, Li B, Allen R, Sparatore A, et al.
Cancer Lett
. 2020 Jun;
488:27-39.
PMID: 32474152
Tumour necrosis factor receptor-associated factor 6 (TRAF6) has been implicated in breast cancer and osteoclastic bone destruction. Here, we report that 6877002, a verified small-molecule inhibitor of TRAF6, reduced metastasis,...
7.
Dennis E, Edwards S, Jackson R, Hartley C, Tsompani D, Capulli M, et al.
J Bone Miner Res
. 2020 Mar;
35(8):1452-1469.
PMID: 32181934
Cysteine-rich with epidermal growth factor (EGF)-like domains 2 (CRELD2) is an endoplasmic reticulum (ER)-resident chaperone highly activated under ER stress in conditions such as chondrodysplasias; however, its role in healthy...
8.
Capulli M, Hristova D, Valbret Z, Carys K, Arjan R, Maurizi A, et al.
Br J Cancer
. 2019 Jun;
121(2):157-171.
PMID: 31239543
Background: Recurrence after >5-year disease-free survival affects one-fifth of breast cancer patients and is the clinical manifestation of cancer cell reactivation after persistent dormancy. Methods: We investigated cellular dormancy in...
9.
Maurizi A, Capulli M, Curle A, Patel R, Ucci A, Cortes J, et al.
Bone Res
. 2019 Jun;
7:17.
PMID: 31231577
Autosomal dominant osteopetrosis type 2 (ADO2) is a high-density brittle bone disease characterized by bone pain, multiple fractures and skeletal-related events, including nerve compression syndrome and hematological failure. We demonstrated...
10.
Marino S, de Ridder D, Bishop R, Renema N, Ponzetti M, Sophocleous A, et al.
EBioMedicine
. 2019 Jun;
44:452-466.
PMID: 31151929
Background: Cancer-associated bone disease is a serious complication in bone sarcomas and metastatic carcinomas of breast and prostate origin. Monoacylglycerol lipase (MAGL) is an enzyme of the endocannabinoid system, and...