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Matthias Zilbauer

Explore the profile of Matthias Zilbauer including associated specialties, affiliations and a list of published articles. Areas
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Articles 83
Citations 2565
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Recent Articles
11.
Krohn L, Azabdaftari A, Heuberger J, Hudert C, Zilbauer M, Breiderhoff T, et al.
Front Immunol . 2023 Oct; 14:1261666. PMID: 37799712
Background And Aims: Intestinal epithelial cells separate the luminal flora from lamina propria immune cells and regulate innate immune responses in the gut. An imbalance of the mucosal immune response...
12.
Skoufou-Papoutsaki N, Adler S, DSantos P, Mannion L, Mehmed S, Kemp R, et al.
Dis Model Mech . 2023 Sep; 16(10). PMID: 37772705
Organoids, combined with genetic editing strategies, have the potential to offer rapid and efficient investigation of gene function in many models of human disease. However, to date, the editing efficiency...
13.
Zilbauer M, James K, Kaur M, Pott S, Li Z, Burger A, et al.
Nat Rev Gastroenterol Hepatol . 2023 May; 20(9):597-614. PMID: 37258747
The number of studies investigating the human gastrointestinal tract using various single-cell profiling methods has increased substantially in the past few years. Although this increase provides a unique opportunity for...
14.
Wang Y, Robinson P, Coorens T, Moore L, Lee-Six H, Noorani A, et al.
Nat Genet . 2023 Jan; 55(2):246-254. PMID: 36702998
APOBEC mutational signatures SBS2 and SBS13 are common in many human cancer types. However, there is an incomplete understanding of its stimulus, when it occurs in the progression from normal...
15.
Caipa Garcia A, Kucab J, Al-Serori H, Beck R, Fischer F, Hufnagel M, et al.
Int J Mol Sci . 2023 Jan; 24(1). PMID: 36614051
Organoids are 3D cultures that to some extent reproduce the structure, composition and function of the mammalian tissues from which they derive, thereby creating in vitro systems with more in...
16.
Ross A, Zilbauer M
J Crohns Colitis . 2022 Nov; 17(2):151-152. PMID: 36367402
No abstract available.
17.
Wesley B, Ross A, Muraro D, Miao Z, Saxton S, Tomaz R, et al.
Nat Cell Biol . 2022 Sep; 24(10):1487-1498. PMID: 36109670
The liver has been studied extensively due to the broad number of diseases affecting its vital functions. However, therapeutic advances have been hampered by the lack of knowledge concerning human...
18.
Edgar R, Perrone F, Foster A, Payne F, Lewis S, Nayak K, et al.
Cell Mol Gastroenterol Hepatol . 2022 Aug; 14(6):1295-1310. PMID: 36038072
Background & Aims: Human intestinal epithelial organoids (IEOs) are a powerful tool to model major aspects of intestinal development, health, and diseases because patient-derived cultures retain many features found in ...
19.
G N, Zilbauer M
Frontline Gastroenterol . 2022 Jul; 13(e1):e22-e27. PMID: 35812027
The global incidence and prevalence of paediatric inflammatory bowel disease (IBD) is increasing, with a notable emergence in developing countries with historically low rates. This suggests that environmental and epigenetic...
20.
Serra E, Schwerd T, Moutsianas L, Cavounidis A, Fachal L, Pandey S, et al.
Nat Commun . 2022 Jun; 13(1):3576. PMID: 35732629
No abstract available.