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Matthias Eibauer

Explore the profile of Matthias Eibauer including associated specialties, affiliations and a list of published articles. Areas
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Articles 21
Citations 840
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Recent Articles
1.
Kechagia Z, Eibauer M, Medalia O
Curr Opin Cell Biol . 2024 Jun; 89:102375. PMID: 38850681
Intermediate filaments (IFs) are integral to the cell cytoskeleton, supporting cellular mechanical stability. Unlike other cytoskeletal components, the detailed structure of assembled IFs has yet to be resolved. This review...
2.
Eibauer M, Weber M, Kronenberg-Tenga R, Beales C, Boujemaa-Paterski R, Turgay Y, et al.
Nat Struct Mol Biol . 2024 Apr; 31(6):939-949. PMID: 38632361
Intermediate filaments (IFs) are integral components of the cytoskeleton. They provide cells with tissue-specific mechanical properties and are involved in numerous cellular processes. Due to their intricate architecture, a 3D...
3.
Chung W, Eibauer M, Li W, Boujemaa-Paterski R, Geiger B, Medalia O
Commun Biol . 2022 Dec; 5(1):1338. PMID: 36473943
Physical interactions of cells with the underlying extracellular matrix (ECM) play key roles in multiple cellular processes. The actin cytoskeleton is a central driver and regulator of cellular dynamics, that...
4.
de Leeuw R, Kronenberg-Tenga R, Eibauer M, Medalia O
Nucleus . 2022 Feb; 13(1):49-57. PMID: 35130129
Lamins are the major constituent of the nuclear lamina, a protein meshwork underlying the inner nuclear membrane. Nuclear lamins are type V intermediate filaments that assemble into ~3.5 nm thick...
5.
Sorrentino S, Conesa J, Cuervo A, Melero R, Martins B, Fernandez-Gimenez E, et al.
Proc Natl Acad Sci U S A . 2021 Sep; 118(37). PMID: 34504018
During activation the platelet cytoskeleton is reorganized, inducing adhesion to the extracellular matrix and cell spreading. These processes are critical for wound healing and clot formation. Initially, this task relies...
6.
Weber M, Eibauer M, Sivagurunathan S, Magin T, Goldman R, Medalia O
Elife . 2021 Jul; 10. PMID: 34323216
Keratin intermediate filaments are an essential and major component of the cytoskeleton in epithelial cells. They form a stable yet dynamic filamentous network extending from the nucleus to the cell...
7.
Kronenberg-Tenga R, Tatli M, Eibauer M, Wu W, Shin J, Bonne G, et al.
J Cell Sci . 2021 Feb; 134(6). PMID: 33536248
The gene encodes the A-type lamins, which polymerize into ∼3.5-nm-thick filaments and, together with B-type lamins and associated proteins, form the nuclear lamina. Mutations in cause a wide variety of...
8.
Martins B, Sorrentino S, Chung W, Tatli M, Medalia O, Eibauer M
Structure . 2021 Jan; 29(5):488-498.e4. PMID: 33476550
The actin cytoskeleton plays a fundamental role in numerous cellular processes, such as cell motility, cytokinesis, and adhesion to the extracellular matrix. Revealing the polarity of individual actin filaments in...
9.
Boujemaa-Paterski R, Martins B, Eibauer M, Beales C, Geiger B, Medalia O
Elife . 2020 Nov; 9. PMID: 33185186
Vinculin plays a fundamental role in integrin-mediated cell adhesion. Activated by talin, it interacts with diverse adhesome components, enabling mechanical coupling between the actin cytoskeleton and the extracellular matrix. Here...
10.
Schmid M, Ernst P, Honegger A, Suomalainen M, Zimmermann M, Braun L, et al.
Nat Commun . 2018 Feb; 9(1):450. PMID: 29386504
Most systemic viral gene therapies have been limited by sequestration and degradation of virions, innate and adaptive immunity, and silencing of therapeutic genes within the target cells. Here we engineer...