Ohad Medalia
Overview
Explore the profile of Ohad Medalia including associated specialties, affiliations and a list of published articles.
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119
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4022
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Recent Articles
1.
Kono Y, Pack C, Ichikawa T, Komatsubara A, Adam S, Miyazawa K, et al.
PNAS Nexus
. 2024 Dec;
3(12):pgae527.
PMID: 39677369
The nuclear lamina (NL) lines the nuclear envelope (NE) to maintain nuclear structure in metazoan cells. The major NL components, the nuclear lamins contribute to the protection against NE rupture...
2.
Wang B, Luo Q, Medalia O
Adv Biol Regul
. 2024 Nov;
95:101059.
PMID: 39547851
The intricate interplay between lamins and chromatin underpins the structural integrity and functional organization of the eukaryotic nucleus. Lamins, type V intermediate filament proteins, form a robust meshwork beneath the...
3.
4.
Coelho-Rato L, Parvanian S, Salajkova S, Medalia O, Eriksson J
J Cell Sci
. 2024 Aug;
137(16).
PMID: 39206824
Intermediate filaments (IFs) comprise a large family of versatile cytoskeletal proteins, divided into six subtypes with tissue-specific expression patterns. IFs have a wide repertoire of cellular functions, including providing structural...
5.
Nuesch M, Pietrek L, Holmstrom E, Nettels D, von Roten V, Kronenberg-Tenga R, et al.
Nat Commun
. 2024 Jul;
15(1):6010.
PMID: 39019880
The conformational dynamics of single-stranded nucleic acids are fundamental for nucleic acid folding and function. However, their elementary chain dynamics have been difficult to resolve experimentally. Here we employ a...
6.
Kechagia Z, Eibauer M, Medalia O
Curr Opin Cell Biol
. 2024 Jun;
89:102375.
PMID: 38850681
Intermediate filaments (IFs) are integral to the cell cytoskeleton, supporting cellular mechanical stability. Unlike other cytoskeletal components, the detailed structure of assembled IFs has yet to be resolved. This review...
7.
Eibauer M, Weber M, Kronenberg-Tenga R, Beales C, Boujemaa-Paterski R, Turgay Y, et al.
Nat Struct Mol Biol
. 2024 Apr;
31(6):939-949.
PMID: 38632361
Intermediate filaments (IFs) are integral components of the cytoskeleton. They provide cells with tissue-specific mechanical properties and are involved in numerous cellular processes. Due to their intricate architecture, a 3D...
8.
Buxboim A, Kronenberg-Tenga R, Salajkova S, Avidan N, Shahak H, Thurston A, et al.
FEBS Lett
. 2023 Oct;
597(22):2791-2805.
PMID: 37813648
Nuclear lamins are type-V intermediate filaments that are involved in many nuclear processes. In mammals, A- and B-type lamins assemble into separate physical meshwork underneath the inner nuclear membrane, the...
9.
Franz F, Tapia-Rojo R, Winograd-Katz S, Boujemaa-Paterski R, Li W, Unger T, et al.
Nat Commun
. 2023 Jul;
14(1):4311.
PMID: 37463895
The talin-vinculin axis is a key mechanosensing component of cellular focal adhesions. How talin and vinculin respond to forces and regulate one another remains unclear. By combining single-molecule magnetic tweezers...
10.
Li W, Chung W, Kozlov M, Medalia O, Geiger B, Bershadsky A
Biophys J
. 2023 Jun;
122(18):3704-3721.
PMID: 37301982
Adherent filopodia are elongated finger-like membrane protrusions, extending from the edges of diverse cell types and participating in cell adhesion, spreading, migration, and environmental sensing. The formation and elongation of...