Matthias Bochtler
Overview
Explore the profile of Matthias Bochtler including associated specialties, affiliations and a list of published articles.
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Articles
101
Citations
1425
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Recent Articles
1.
Bochtler M
Bioessays
. 2024 Oct;
47(1):e2400155.
PMID: 39404756
The performance of deep Neural Networks (NNs) in the text (ChatGPT) and image (DALL-E2) domains has attracted worldwide attention. Convolutional NNs (CNNs), Large Language Models (LLMs), Denoising Diffusion Probabilistic Models...
2.
Szafran K, Rafalski D, Skowronek K, Wojciechowski M, Kazrani A, Gilski M, et al.
Nucleic Acids Res
. 2024 Jul;
52(15):9103-9118.
PMID: 39041409
The BisI family of restriction endonucleases is unique in requiring multiple methylated or hydroxymethylated cytosine residues within a short recognition sequence (GCNGC), and in cleaving directly within this sequence, rather...
3.
4.
Wojciechowski M, Czapinska H, Krwawicz J, Rafalski D, Bochtler M
Nucleic Acids Res
. 2024 Jul;
52(15):9267-9281.
PMID: 38966999
DNA methyltransferases are drug targets for myelodysplastic syndrome (MDS), chronic myelomonocytic leukemia (CMML), acute myelogenous leukemia (AML) and possibly β-hemoglobinopathies. We characterize the interaction of nucleoside analogues in DNA with...
5.
Helbrecht I, Heiter D, Yang W, Vincze T, Hanneman A, Lutz T, et al.
Front Microbiol
. 2024 Apr;
15:1286822.
PMID: 38655080
Winged helix (wH) domains, also termed winged helix-turn-helix (wHTH) domains, are widespread in all kingdoms of life and have diverse roles. In the context of DNA binding and DNA modification...
6.
Zhang D, Czapinska H, Bochtler M, Wlodawer A, Lubkowski J
Protein Sci
. 2024 Mar;
33(4):e4920.
PMID: 38501449
L-Asparaginases (ASNases) catalyze the hydrolysis of L-Asn to L-Asp and ammonia. Members of the ASNase family are used as drugs in the treatment of leukemia, as well as in the...
7.
Bochtler M
Structure
. 2024 Feb;
32(5):630-643.e6.
PMID: 38412856
X-rays, electrons, and neutrons probe different properties of matter. X-rays feel electron density (ED). Electrons sense the electrostatic potential (ESP) of electrons and nuclei. Neutrons are sensitive to nuclear coherent...
8.
Szczesniak K, Veillard F, Scavenius C, Chudzik K, Ferenc K, Bochtler M, et al.
mBio
. 2023 Sep;
14(5):e0098023.
PMID: 37750700
Exclusively in the Bacteroidetes phylum, most proteins exported across the inner membrane via the Sec system and released into the periplasm by type I signal peptidase have N-terminal glutamine converted...
9.
Fantuzzi A, Haniewicz P, Farci D, Loi M, Park K, Buchel C, et al.
Plant Physiol
. 2023 May;
192(4):2656-2671.
PMID: 37202365
In thylakoid membranes, photosystem II (PSII) monomers from the stromal lamellae contain the subunits PsbS and Psb27 (PSIIm-S/27), while PSII monomers (PSIIm) from granal regions lack these subunits. Here, we...
10.
Stroynowska-Czerwinska A, Klimczak M, Pastor M, Kazrani A, Misztal K, Bochtler M
Cell Mol Life Sci
. 2023 Jan;
80(1):23.
PMID: 36598580
Histone lysine-specific methyltransferase 2 (KMT2A-D) proteins, alternatively called mixed lineage leukemia (MLL1-4) proteins, mediate positive transcriptional memory. Acting as the catalytic subunits of human COMPASS-like complexes, KMT2A-D methylate H3K4 at...