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Matthew R Sharpe

Explore the profile of Matthew R Sharpe including associated specialties, affiliations and a list of published articles. Areas
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Articles 16
Citations 930
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Recent Articles
1.
Woolbright B, Nguyen N, McGill M, Sharpe M, Curry S, Jaeschke H
Toxicol Lett . 2022 Jul; 367:59-66. PMID: 35905941
Acetaminophen (APAP) overdose causes liver injury in animals and humans. Although well-studied in animals, limited longitudinal data exist on cytokine release after APAP overdose in patients. The purpose of this...
2.
Burnett D, Sharpe M
Respir Care . 2021 Nov; 66(12):1929-1931. PMID: 34789520
No abstract available.
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Ellerbeck E, Nollen N, Hutcheson T, Phadnis M, Fitzgerald S, Vacek J, et al.
JAMA Netw Open . 2019 Jan; 1(5):e181843. PMID: 30646142
Importance: Smokers with chronic obstructive pulmonary disease (COPD) have particular difficulty quitting. Long-term nicotine replacement therapy (LT-NRT) might offer a strategy for reducing harm from cigarettes and provide a pathway...
5.
Weemhoff J, Woolbright B, Jenkins R, McGill M, Sharpe M, Olson J, et al.
Liver Int . 2016 Jul; 37(3):377-384. PMID: 27429052
Background & Aims: Hypoxic hepatitis is a clinical condition precipitated by prolonged periods of oxygen deprivation to the liver. It can have several underlying causes. Despite its prevalence in critically...
6.
Burnett D, Vardiman J, Deckert J, Ward J, Sharpe M
Respir Care . 2016 Mar; 61(7):897-901. PMID: 27006350
Background: Exercise-induced bronchoconstriction (EIB) can lead to long-term respiratory illness and even death. EIB prevalence rates are both high and variable in college athletes. Also, prevalence rates may be underestimated...
7.
Diederich E, Mahnken J, Rigler S, Williamson T, Tarver S, Sharpe M
Simul Healthc . 2015 Nov; 10(6):360-367. PMID: 26536341
Introduction: Simulation-based education for central venous catheter (CVC) insertion has been repeatedly documented to improve performance, but the impact of simulation model fidelity has not been described. The aim of...
8.
Xie Y, McGill M, Cook S, Sharpe M, Winefield R, Wilkins D, et al.
Xenobiotica . 2015 Apr; 45(10):921-9. PMID: 25869248
1. It has been suggested that acetaminophen (APAP)-protein adducts can be measured in circulation to diagnose APAP-induced liver injury. However, the full-time course of plasma adducts has not been studied...
9.
Woolbright B, McGill M, Staggs V, Winefield R, Gholami P, Olyaee M, et al.
Toxicol Sci . 2014 Sep; 142(2):436-44. PMID: 25239633
Acetaminophen (APAP)-induced acute liver failure (ALF) remains a major clinical problem. Although a majority of patients recovers after severe liver injury, a subpopulation of patients proceeds to ALF. Bile acids...
10.
McGill M, Staggs V, Sharpe M, Lee W, Jaeschke H
Hepatology . 2014 Jun; 60(4):1336-45. PMID: 24923598
Unlabelled: Acetaminophen (APAP) overdose is a major cause of acute liver failure (ALF). Numerous studies have shown that APAP hepatotoxicity in mice involves mitochondrial dysfunction, and recent data suggest that...