Matthew L Edin
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Explore the profile of Matthew L Edin including associated specialties, affiliations and a list of published articles.
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106
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2526
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Recent Articles
1.
Welch B, Bommarito P, Cantonwine D, Milne G, Stevens D, Edin M, et al.
Environ Sci Technol
. 2025 Feb;
59(6):2987-2999.
PMID: 39913660
Consumer product chemicals pose an environmental risk to public health. Exposure during pregnancy to consumer product chemicals, particularly phthalates and phenols, may increase the susceptibility to pregnancy disorders by dysregulating...
2.
Darwesh A, Fang L, Altamimi T, Jamieson K, Bassiouni W, Valencia R, et al.
Cardiovasc Res
. 2024 Dec;
PMID: 39658136
Aims: Although current clinical therapies following myocardial infarction have improved patient outcomes, morbidity, and mortality rates secondary to ischemic and ischemia reperfusion (IR) injury remains high. Maintaining mitochondrial quality is...
3.
Li H, House J, Nichols C, Gruzdev A, Ward J, Li J, et al.
Lung
. 2024 Aug;
202(5):659-672.
PMID: 39153120
Purpose: Over 550 loci have been associated with human pulmonary function in genome-wide association studies (GWAS); however, the causal role of most remains uncertain. Single nucleotide polymorphisms in a disintegrin...
4.
Foo A, Edin M, Lin W, Lih F, Gabel S, Uddin M, et al.
Biochemistry
. 2024 Jun;
63(14):1730-1737.
PMID: 38915291
The cockroach allergen Bla g 1 encloses an exceptionally large hydrophobic cavity, which allows it to bind and deliver unsaturated fatty acid ligands. Bla g 1-mediated delivery of naturally occurring...
5.
Edin M, Gruzdev A, Graves J, Lih F, Morisseau C, Ward J, et al.
FASEB J
. 2024 May;
38(10):e23692.
PMID: 38786655
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection involves an initial viral infection phase followed by a host-response phase that includes an eicosanoid and cytokine storm, lung inflammation and respiratory...
6.
Edin M, Gruzdev A, Bradbury J, Graves J, Muse G, Goulding D, et al.
Biochem Pharmacol
. 2024 Apr;
228:116237.
PMID: 38679211
Cytochromes P450 can metabolize endogenous fatty acids, such as arachidonic acid, to bioactive lipids such as epoxyeicosatrienoic acids (EETs) that have beneficial effects. EETs protect hearts against ischemic damage, heart...
7.
Hateley C, Olona A, Halliday L, Edin M, Ko J, Forlano R, et al.
EBioMedicine
. 2024 Apr;
103:105127.
PMID: 38677183
Background: Obesity drives maladaptive changes in the white adipose tissue (WAT) which can progressively cause insulin resistance, type 2 diabetes mellitus (T2DM) and metabolic dysfunction-associated liver disease (MASLD). Obesity-mediated loss...
8.
Li H, Bradbury J, Edin M, Gruzdev A, Li H, Graves J, et al.
J Clin Invest
. 2024 Mar;
134(9).
PMID: 38483511
In lung, thromboxane A2 (TXA2) activates the TP receptor to induce proinflammatory and bronchoconstrictor effects. Thus, TP receptor antagonists and TXA2 synthase inhibitors have been tested as potential asthma therapeutics...
9.
Panigrahy D, Kelly A, Wang W, Yang J, Hwang S, Gillespie M, et al.
bioRxiv
. 2024 Mar;
PMID: 38463975
Previous studies have implicated persistent innate immune signaling in the pathogenesis of arrhythmogenic cardiomyopathy (ACM), a familial non-ischemic heart muscle disease characterized by life-threatening arrhythmias and progressive myocardial injury. Here,...
10.
Williams L, Hamilton M, Edin M, Lih F, Eccles-Miller J, Tharayil N, et al.
Toxics
. 2024 Feb;
12(2).
PMID: 38393201
Perfluorooctanesulfonate (PFOS) is a widespread environmental pollutant with a long half-life and clearly negative outcomes on metabolic diseases such as fatty liver disease and diabetes. Male and female Cyp2b-null and...