Nupur Dasgupta
Overview
Explore the profile of Nupur Dasgupta including associated specialties, affiliations and a list of published articles.
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Articles
20
Citations
385
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Recent Articles
1.
Oatman N, Dasgupta N, Arora P, Choi K, Gawali M, Gupta N, et al.
Sci Adv
. 2021 Feb;
7(7.
PMID: 33568479
The lipogenic enzyme stearoyl CoA desaturase (SCD) plays a key role in tumor lipid metabolism and membrane architecture. SCD is often up-regulated and a therapeutic target in cancer. Here, we...
2.
Zahedi K, Brooks M, Barone S, Rahmati N, Stewart T, Dunworth M, et al.
J Neuroinflammation
. 2020 Oct;
17(1):301.
PMID: 33054763
Background: Polyamine catabolism plays a key role in maintaining intracellular polyamine pools, yet its physiological significance is largely unexplored. Here, we report that the disruption of polyamine catabolism leads to...
3.
McDaniel C, Panmanee W, Winsor G, Gill E, Bertelli C, Schurr M, et al.
Proc Natl Acad Sci U S A
. 2020 Feb;
117(9):4921-4930.
PMID: 32071223
Antibiotic-resistant superbug bacteria represent a global health problem with no imminent solutions. Here we demonstrate that the combination (termed AB569) of acidified nitrite (A-NO) and Na-EDTA (disodium ethylenediaminetetraacetic acid) inhibited...
4.
Woodle E, Tremblay S, Brailey P, Girnita A, Alloway R, Aronow B, et al.
Am J Transplant
. 2019 Oct;
20(2):399-410.
PMID: 31595669
Donor-specific antibodies (DSAs) have a deleterious effect on allografts and remain a major immunologic barrier in transplantation. Current therapies to eliminate DSAs are ineffective in highly HLA-sensitized patients. Proteasome inhibitors...
5.
Flood H, Bolte C, Dasgupta N, Sharma A, Zhang Y, Gandhi C, et al.
Biol Open
. 2019 Jan;
8(2).
PMID: 30670377
Hepatic fibrosis is the common end stage to a variety of chronic liver injuries and is characterized by an excessive deposition of extracellular matrix (ECM), which disrupts the liver architecture...
6.
Chhipa R, Fan Q, Anderson J, Muraleedharan R, Huang Y, Ciraolo G, et al.
Nat Cell Biol
. 2018 Sep;
20(11):1328.
PMID: 30190576
In the version of this Article originally published, in ref. 34 the first author's name was spelled incorrectly. The correct reference is: Rodón, L. et al. Active CREB1 promotes a...
7.
Ikeda K, Hale P, Pauciulo M, Dasgupta N, Pastura P, Le Cras T, et al.
Am J Respir Cell Mol Biol
. 2018 Aug;
60(1):106-116.
PMID: 30134121
Patients with pulmonary arterial hypertension (PAH) can harbor mutations in several genes, most commonly in BMPR2. However, disease penetrance in patients with BMPR2 mutations is low. In addition, most patients...
8.
Chhipa R, Fan Q, Anderson J, Muraleedharan R, Huang Y, Ciraolo G, et al.
Nat Cell Biol
. 2018 Aug;
20(10):1228.
PMID: 30089841
In the version of this Article originally published, the competing interests statement was missing. The authors declare no competing interests; this statement has now been added in all online versions...
9.
Chhipa R, Fan Q, Anderson J, Muraleedharan R, Huang Y, Ciraolo G, et al.
Nat Cell Biol
. 2018 Jun;
20(7):823-835.
PMID: 29915361
Stress is integral to tumour evolution, and cancer cell survival depends on stress management. We found that cancer-associated stress chronically activates the bioenergetic sensor AMP kinase (AMPK) and, to survive,...
10.
Schafer C, Moore V, Dasgupta N, Javadov S, James J, Glukhov A, et al.
Front Pharmacol
. 2018 Apr;
9:318.
PMID: 29695963
Tafazzin knockdown (TazKD) in mice is widely used to create an experimental model of Barth syndrome (BTHS) that exhibits dilated cardiomyopathy and impaired exercise capacity. Peroxisome proliferator-activated receptors (PPARs) are...