Matthew Jarpe
Overview
Explore the profile of Matthew Jarpe including associated specialties, affiliations and a list of published articles.
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22
Citations
1173
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Recent Articles
1.
Pryce K, Serafini R, Ramakrishnan A, Nicolais A, Giosan I, Polizu C, et al.
Nat Neurosci
. 2024 Jan;
27(2):384.
PMID: 38253639
No abstract available.
2.
Michelson D, Chin W, Dworkin R, Freeman R, Herrmann D, Mazitschek R, et al.
Pain Rep
. 2023 Oct;
8(6):e1114.
PMID: 37899940
Introduction: Current treatments for painful diabetic peripheral neuropathy (DPN) are insufficiently effective for many individuals and do not treat nonpain signs and symptoms. The enzyme histone deacetylase type 6 (HDAC6)...
3.
Braz S, Morgado M, Pereira M, Monteiro A, Golonzhka O, Jarpe M, et al.
Front Mol Neurosci
. 2023 Aug;
16:1231659.
PMID: 37588057
Introduction: In Krabbe disease (KD), mutations in β-galactosylceramidase (GALC), a lysosomal enzyme responsible for the catabolism of galactolipids, leads to the accumulation of its substrates galactocerebroside and psychosine. This neurologic...
4.
Pryce K, Serafini R, Ramakrishnan A, Nicolais A, Giosan I, Polizu C, et al.
Nat Neurosci
. 2023 Jun;
26(7):1229-1244.
PMID: 37291337
The development of physical dependence and addiction disorders due to misuse of opioid analgesics is a major concern with pain therapeutics. We developed a mouse model of oxycodone exposure and...
5.
Sakloth F, Manouras L, Avrampou K, Mitsi V, Serafini R, Pryce K, et al.
Psychopharmacology (Berl)
. 2020 May;
237(7):2139-2149.
PMID: 32388618
Background: HDAC6 is a class IIB histone deacetylase expressed at many levels of the nociceptive pathway. This study tested the ability of novel and selective HDAC6 inhibitors to alleviate sensory...
6.
Ren J, Catalina M, Eden K, Liao X, Read K, Luo X, et al.
Front Immunol
. 2019 Nov;
10:2512.
PMID: 31708928
Autoantibody production by plasma cells (PCs) plays a pivotal role in the pathogenesis of systemic lupus erythematosus (SLE). The molecular pathways by which B cells become pathogenic PC secreting autoantibodies...
7.
Rossaert E, Pollari E, Jaspers T, Van Helleputte L, Jarpe M, Van Damme P, et al.
Acta Neuropathol Commun
. 2019 Jul;
7(1):107.
PMID: 31277703
Dysregulation of epigenetic mechanisms is emerging as a central event in neurodegenerative disorders, including amyotrophic lateral sclerosis (ALS). In many models of neurodegeneration, global histone acetylation is decreased in the...
8.
Gewandter J, Brell J, Cavaletti G, Dougherty P, Evans S, Howie L, et al.
Neurology
. 2018 Jul;
91(9):403-413.
PMID: 30054438
Chemotherapy-induced peripheral neuropathy (CIPN) is a common and potentially dose-limiting side effect of neurotoxic chemotherapies. No therapies are available to prevent CIPN. The small number of positive randomized clinical trials...
9.
Majid T, Griffin D, Criss 2nd Z, Jarpe M, Pautler R
Alzheimers Dement (N Y)
. 2018 Jun;
1(3):170-181.
PMID: 29854936
Introduction: Current therapy for Alzheimer's disease (AD) focuses on delaying progression, illustrating the need for more effective therapeutic targets. Histone deacetylase 6 (HDAC6) modulates tubulin acetylation and has been implicated...
10.
Van Helleputte L, Kater M, Cook D, Eykens C, Rossaert E, Haeck W, et al.
Neurobiol Dis
. 2017 Dec;
111:59-69.
PMID: 29197621
As cancer is becoming more and more a chronic disease, a large proportion of patients is confronted with devastating side effects of certain anti-cancer drugs. The most common neurological complications...