Matthew J Ellington
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Explore the profile of Matthew J Ellington including associated specialties, affiliations and a list of published articles.
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76
Citations
4166
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Recent Articles
11.
Mushtaq S, Vickers A, Doumith M, Ellington M, Woodford N, Livermore D
J Antimicrob Chemother
. 2020 Dec;
76(1):160-170.
PMID: 33305800
Background: Boronates are of growing interest as β-lactamase inhibitors. The only marketed analogue, vaborbactam, principally targets KPC carbapenemases, but taniborbactam (VNRX-5133, Venatorx) has a broader spectrum. Methods: MICs of cefepime...
12.
Duggett N, Ellington M, Hopkins K, Ellaby N, Randall L, Lemma F, et al.
J Antimicrob Chemother
. 2020 Oct;
76(1):263-265.
PMID: 33068401
No abstract available.
13.
Rawson T, Moore L, Castro-Sanchez E, Charani E, Davies F, Satta G, et al.
J Antimicrob Chemother
. 2020 May;
75(7):1681-1684.
PMID: 32433765
The emergence of the Severe Acute Respiratory Syndrome coronavirus 2 (SARS-CoV-2) has required an unprecedented response to control the spread of the infection and protect the most vulnerable within society....
14.
Stoesser N, Phan H, Seale A, Aiken Z, Thomas S, Smith M, et al.
Antimicrob Agents Chemother
. 2020 Feb;
64(5).
PMID: 32094139
Carbapenem resistance in is a public health threat. carbapenemase (encoded by alleles of the family) is one of the most common transmissible carbapenem resistance mechanisms worldwide. The dissemination of historically...
15.
Doyle R, OSullivan D, Aller S, Bruchmann S, Clark T, Pelegrin A, et al.
Microb Genom
. 2020 Feb;
6(2).
PMID: 32048983
Antimicrobial resistance (AMR) poses a threat to public health. Clinical microbiology laboratories typically rely on culturing bacteria for antimicrobial-susceptibility testing (AST). As the implementation costs and technical barriers fall, whole-genome...
16.
Ellington M, Davies F, Jauneikaite E, Hopkins K, Turton J, Adams G, et al.
Clin Infect Dis
. 2019 Nov;
71(10):2553-2560.
PMID: 31746994
Background: Early and accurate treatment of infections due to carbapenem-resistant organisms is facilitated by rapid diagnostics, but rare resistance mechanisms can compromise detection. One year after a Guiana Extended-Spectrum (GES)-5...
17.
Day M, Hopkins K, Wareham D, Toleman M, Elviss N, Randall L, et al.
Lancet Infect Dis
. 2019 Oct;
19(12):1325-1335.
PMID: 31653524
Background: Extended-spectrum β-lactamase-producing Escherichia coli isolates (ESBL-E coli) cause more than 5000 cases of bacteraemias annually in the UK. The contribution of the food chain to these infections is debated....
18.
Ellaby N, Doumith M, Hopkins K, Woodford N, Ellington M
Euro Surveill
. 2019 Sep;
24(37).
PMID: 31530344
Background ST131, a global, high-risk clone, comprises fluoroquinolone resistance (FQ-R) mutations and CTX-M extended-spectrum beta-lactamases associated with the 30-encoding clades, C1 and C2. Further carbapenem resistance development in ST131 is...
19.
Ellington M, Heinz E, Wailan A, Dorman M, de Goffau M, Cain A, et al.
Genome Biol
. 2019 Sep;
20(1):184.
PMID: 31477167
Background: Two of the most important pathogens contributing to the global rise in antimicrobial resistance (AMR) are Klebsiella pneumoniae and Enterobacter cloacae. Despite this, most of our knowledge about the...
20.
Mosavie M, Blandy O, Jauneikaite E, Caldas I, Ellington M, Woodford N, et al.
BMC Res Notes
. 2019 Jun;
12(1):335.
PMID: 31196206
Objective: The increase in Escherichia coli bloodstream infections mandates better characterisation of the relationship between commensal and invasive isolates. This study adopted a simple approach to characterize E. coli in...