Matthew J Bottomley
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Explore the profile of Matthew J Bottomley including associated specialties, affiliations and a list of published articles.
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58
Citations
1928
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Recent Articles
1.
Zibandeh N, Li Z, Ogg G, Bottomley M
Front Immunol
. 2024 Oct;
15:1464338.
PMID: 39399503
Chronic kidney disease affects 1 in 10 people globally, with a prevalence twenty times that of cancer. A subset of individuals will progress to end-stage renal disease (ESRD) where renal...
2.
Sponholtz M, Byrne P, Lee A, Ramamohan A, Goldsmith J, McCool R, et al.
Proc Natl Acad Sci U S A
. 2024 Sep;
121(37):e2404250121.
PMID: 39231203
Human cytomegalovirus (HCMV) glycoprotein B (gB) is a class III membrane fusion protein required for viral entry. HCMV vaccine candidates containing gB have demonstrated moderate clinical efficacy, but no HCMV...
3.
Kumaran G, Carroll L, Muirhead N, Bottomley M
J Invest Dermatol
. 2024 Aug;
145(3):522-535.
PMID: 39177547
Spatial transcriptomic (ST) profiling is the mapping of gene expression within cell populations with preservation of positional context and represents an exciting new approach to develop our understanding of local...
4.
Veggi D, Chesterman C, Santini L, Huang Y, Pacchiani N, Sierra J, et al.
FASEB Bioadv
. 2024 Aug;
6(8):235-248.
PMID: 39114449
Thousands of disease cases and hundreds of deaths occur globally each year due to invasive meningococcal disease. serogroup B (MenB) is the leading cause of such disease in developed countries....
5.
Ahuja S, Manoharan M, Lee G, McKinnon L, Meunier J, Steri M, et al.
Nat Commun
. 2023 Jun;
14(1):3286.
PMID: 37311745
Some people remain healthier throughout life than others but the underlying reasons are poorly understood. Here we hypothesize this advantage is attributable in part to optimal immune resilience (IR), defined...
6.
Tseng C, Roddick A, Bottomley M, Shapiro S, Udayaraj U
EJHaem
. 2023 Feb;
4(1):291-293.
PMID: 36819183
No abstract available.
7.
Haag A, Liljeroos L, Donato P, Pozzi C, Brignoli T, Bottomley M, et al.
Microbiol Spectr
. 2023 Jan;
11(1):e0257422.
PMID: 36688711
Staphylococcus aureus is a clinically important bacterial pathogen that has become resistant to treatment with most routinely used antibiotics. Alternative strategies, such as vaccination and phage therapy, are therefore actively...
8.
Bottomley M, Beckwith H, McMahon A, Nation M, Wheeler D, Greenwood S, et al.
BMJ Open
. 2022 Dec;
12(12):e066212.
PMID: 36517087
Objectives: To establish barriers and motivators underlying research engagement among early-career practitioners in nephrology across the UK, in order to guide potential interventions to enhance research involvement in renal units....
9.
Bottomley M, Massey P, Thuraisingham R, Doyle A, Rao S, Bibee K, et al.
Transpl Int
. 2022 Dec;
35:10880.
PMID: 36484063
Cutaneous squamous cell carcinoma (CSCC) is a major cause of morbidity and mortality after organ transplant. Many patients subsequently develop multiple CSCC following a first CSCC, and the risk of...
10.
Bottomley M, Harden P, Wood K, Hester J, Issa F
Front Immunol
. 2022 Jul;
13:901273.
PMID: 35844527
Background: Malignancy is a major cause of morbidity and mortality in transplant recipients. Identification of those at highest risk could facilitate pre-emptive intervention such as reduction of immunosuppression. Reduced circulating...