Matthew J Bottomley
Overview
Explore the profile of Matthew J Bottomley including associated specialties, affiliations and a list of published articles.
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58
Citations
1928
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Recent Articles
11.
Veggi D, Malito E, Lo Surdo P, Pansegrau W, Rippa V, Wahome N, et al.
Comput Struct Biotechnol J
. 2022 May;
20:2070-2081.
PMID: 35601959
Invasive meningococcal disease can cause fatal sepsis and meningitis and is a global health threat. Factor H binding protein (fHbp) is a protective antigen included in the two currently available...
12.
Madge O, Brodey A, Bowen J, Nicholson G, Sivakumar S, Bottomley M
J Clin Med
. 2022 May;
11(9).
PMID: 35566700
The COVID-19 pandemic has hugely disrupted healthcare provision, including oncology services. To evaluate the effects of the pandemic on referral routes leading to diagnosis, treatments, and prognosis in patients with...
13.
Gaied J, Skinner J, Winterbottom C, Brook M, Thornley A, Turner C, et al.
Hemodial Int
. 2021 Dec;
26(2):278-280.
PMID: 34914167
No abstract available.
14.
Bottomley M, Brook M, Shankar S, Hester J, Issa F
Trends Immunol
. 2021 Nov;
43(1):8-21.
PMID: 34844848
Organ transplantation is a modern medical success story. However, since its inception it has been limited by the need for pharmacological immunosuppression. Regulatory cellular therapies offer an attractive solution to...
15.
Andreano E, Paciello I, Bardelli M, Tavarini S, Sammicheli C, Frigimelica E, et al.
EMBO Mol Med
. 2021 May;
13(6):e14035.
PMID: 33998144
Respiratory syncytial virus (RSV) is the leading cause of death from lower respiratory tract infection in infants and children, and is responsible for considerable morbidity and mortality in older adults....
16.
Veggi D, Bianchi F, Santini L, Lo Surdo P, Chesterman C, Pansegrau W, et al.
PLoS Pathog
. 2020 Oct;
16(10):e1008882.
PMID: 33007046
Neisseria meningitidis serogroup B (MenB) is the leading cause of meningococcal meningitis and sepsis in industrialized countries, with the highest incidence in infants and adolescents. Two recombinant protein vaccines that...
17.
McKenna S, Malito E, Rouse S, Abate F, Bensi G, Chiarot E, et al.
Comput Struct Biotechnol J
. 2020 Apr;
18:650-660.
PMID: 32257048
Over 18 million disease cases and half a million deaths worldwide are estimated to be caused annually by Group A Streptococcus. A vaccine to prevent GAS disease is urgently needed....
18.
Bianchi F, Veggi D, Santini L, Buricchi F, Bartolini E, Lo Surdo P, et al.
FASEB J
. 2019 Aug;
33(11):12099-12111.
PMID: 31442074
The 4 component meningococcus B vaccine (4CMenB) vaccine is the first vaccine containing recombinant proteins licensed for the prevention of invasive meningococcal disease caused by meningococcal serogroup B strains. 4CMenB...
19.
Bottomley M, Thomson J, Harwood C, Leigh I
Int J Mol Sci
. 2019 Apr;
20(8).
PMID: 31022866
Cutaneous squamous cell carcinoma (cSCC) is the second most common skin cancer. In immunosuppressed populations it is a source of considerable morbidity and mortality due to its enhanced recurrence and...
20.
Liguori A, Iacono L, Maruggi G, Benucci B, Merola M, Lo Surdo P, et al.
mBio
. 2018 Oct;
9(5).
PMID: 30327444
serogroup B (MenB) is a major cause of sepsis and invasive meningococcal disease. A multicomponent vaccine, 4CMenB, is approved for protection against MenB. Neisserial adhesin A (NadA) is one of...