Matthew I Gibson
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Explore the profile of Matthew I Gibson including associated specialties, affiliations and a list of published articles.
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176
Citations
2500
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Recent Articles
1.
Alobaid M, Richards S, Alexander M, Gibson M, Ghaemmaghami A
Mater Today Bio
. 2024 Dec;
29:101371.
PMID: 39698001
Dendritic cells (DCs) have emerged as a promising target for drug delivery and immune modulation due to their pivotal role in initiating the adaptive immune response. Gold nanoparticles (AuNPs) have...
2.
Gao Y, Bissoyi A, Guo Q, Gibson M
ACS Biomater Sci Eng
. 2024 Sep;
11(1):208-212.
PMID: 39315639
Spheroids and other 3D cellular models more accurately recapitulate physiological responses when compared to 2D models and represent potential alternatives to animal testing. The cryopreservation of spheroids remains challenging, limiting...
3.
Murray A, Kilbride P, Gibson M
RSC Med Chem
. 2024 Sep;
15(9):2980-2995.
PMID: 39309363
Cryopreservation is crucial to fields including immune and stem cell therapies, reproductive technology, blood banking, regenerative medicine and across all biotechnology. During cryopreservation, cryoprotectants are essential to protect cells from...
4.
Hewson A, Lloyd-Laney H, Keenan T, Richards S, Gibson M, Linclau B, et al.
Chem Sci
. 2024 Sep;
PMID: 39282644
Glycans play a major role in biological cell-cell recognition and signal transduction but have found limited application in biosensors due to glycan/lectin promiscuity; multiple proteins are capable of binding to...
5.
Warren M, Biggs C, Bissoyi A, Gibson M, Sosso G
Nat Commun
. 2024 Sep;
15(1):8082.
PMID: 39278938
Controlling the formation and growth of ice is essential to successfully cryopreserve cells, tissues and biologics. Current efforts to identify materials capable of modulating ice growth are guided by iterative...
6.
Hollingsworth K, Di Maio A, Richards S, Vendeville J, Wheatley D, Council C, et al.
Nat Commun
. 2024 Sep;
15(1):7925.
PMID: 39271664
Glycan-mediated interactions play a crucial role in biology and medicine, influencing signalling, immune responses, and disease pathogenesis. However, the use of glycans in biosensing and diagnostics is limited by cross-reactivity,...
7.
Tang Q, Tomas R, Gibson M
Chem Sci
. 2024 Sep;
PMID: 39263661
Non-viral gene delivery with cationic polymers/nanoparticles relies on iterative optimization of the carrier to achieve delivery. Here we demonstrate, instead, that precision engineering of cell surfaces to covalently capture a...
8.
Marton H, Sagona A, Kilbride P, Gibson M
RSC Appl Polym
. 2024 Aug;
2(6):1082-1090.
PMID: 39184364
Bacteriophages are promising as therapeutics and biotechnological tools, but they also present a problem for routine and commercial bacterial cultures, where contamination must be avoided. Poly(carboxylic acids) have been reported...
9.
Nagorska A, Tomas R, Tasnim A, Robb N, Gibson M
Biomacromolecules
. 2024 Jul;
25(8):5352-5358.
PMID: 39051654
Plaque assays quantify the amount of active, replicating virus to study and detect infectious diseases by application of samples to monolayers of cultured cells. Due to the time taken in...
10.
Bianco S, Hasan M, Ahmad A, Richards S, Dietrich B, Wallace M, et al.
Nature
. 2024 Jul;
631(8021):544-548.
PMID: 39020036
A long-standing challenge is how to formulate proteins and vaccines to retain function during storage and transport and to remove the burdens of cold-chain management. Any solution must be practical...