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Matthew H Herynk

Explore the profile of Matthew H Herynk including associated specialties, affiliations and a list of published articles. Areas
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Articles 19
Citations 712
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Recent Articles
11.
Herynk M, Fuqua S
Adv Exp Med Biol . 2007 Nov; 608:130-43. PMID: 17993238
Estrogen and its receptors alpha and beta (ERalpha and ERbeta) play a major role in tumor progression and approximately two-thirds of breast cancers express these functional receptors. Thus, the ER...
12.
Herynk M, Zhang J, Parikh N, Gallick G
J Exp Ther Oncol . 2007 Jun; 6(3):205-17. PMID: 17552361
Overexpression and/or activation of c-Met, the protein tyrosine kinase receptor for the hepatocyte growth factor/scatter factor (HGF/SF), and the protein tyrosine kinase, Src, have been implicated in the progression and...
13.
Herynk M, Parra I, Cui Y, Beyer A, Wu M, Hilsenbeck S, et al.
Clin Cancer Res . 2007 Jun; 13(11):3235-43. PMID: 17545528
Purpose: Estrogen receptor alpha (ERalpha) predicts the natural history of breast cancer without intervening therapy. Here, we have optimized the detection of a somatic mutation, an A908G transition of ERalpha,...
14.
Herynk M, Beyer A, Cui Y, Weiss H, Anderson E, Green T, et al.
Mol Cancer Ther . 2006 Dec; 5(12):3023-31. PMID: 17172405
It has long been appreciated that estrogenic signaling contributes to breast cancer progression. c-Src is also required for a number of processes involved in tumor progression and metastasis. We have...
15.
Minard M, Herynk M, Collard J, Gallick G
Oncogene . 2005 Mar; 24(15):2568-73. PMID: 15735692
Alterations in migration and adhesion are critical to invasion and metastasis. To examine signaling pathways important for colon tumor metastasis, cells of increased migratory potential from the low migratory SW480...
16.
Herynk M, Fuqua S
Endocr Rev . 2004 Dec; 25(6):869-98. PMID: 15583021
As early as the 1800s, the actions of estrogen have been implicated in the development and progression of breast cancer. The estrogen receptor (ER) was identified in the late 1950s...
17.
Kim S, Johnson M, Koterba K, Herynk M, Uehara H, Gallick G
Clin Cancer Res . 2003 Nov; 9(14):5161-70. PMID: 14613995
Purpose: The expression of c-Met, the receptor protein tyrosine kinase for hepatocyte growth factor/scatter factor, frequently increases during prostate tumor progression. However, whether reduced c-Met expression inhibits tumor growth and...
18.
Herynk M, Tsan R, Radinsky R, Gallick G
Clin Exp Metastasis . 2003 Jul; 20(4):291-300. PMID: 12856716
Increased expression and/or activity of c-Met, the receptor protein tyrosine kinase for hepatocyte growth factor/scatter factor, occurs commonly during colon tumor progression. To examine potential roles for c-Met in promoting...
19.
Herynk M, Stoeltzing O, Reinmuth N, Parikh N, Abounader R, Laterra J, et al.
Cancer Res . 2003 Jun; 63(11):2990-6. PMID: 12782608
Overexpression of c-Met, the protein tyrosine kinase receptor for the hepatocyte growth factor/scatter factor, has been implicated in the progression and metastasis of human colorectal carcinoma. To examine the role...